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How to get fromColumbus to Knoxvilleby taxi, plane, bus (Greyhound), car, or bus

Find Transport to Knoxville

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There are 5 ways to get from Columbus to Knoxville by taxi, plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Indianapolis, fly

    best
    1. Take the taxi from Columbus to Indianapolis-Airport-INDtaxi taxi
    2. Fly from Indianapolis (IND) to Mcghee Tyson Airport (TYS)plane plane IND - TYS
    4h 33m
    $298–966

  2. Drive 303.1 mi

    cheapest
    1. Drive from Columbus to Knoxvillecar car 303.1 mi
    5h 38m
    $56–80

  3. Bus

    1. Take the bus from TA Travel Center - Seymour to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    37h 19m
    $388–672

  4. Drive to Covington, fly

    1. Drive from Columbus to Covington (CVG)car car
    2. Fly from Covington (CVG) to Mcghee Tyson Airport (TYS)plane plane CVG - TYS
    5h 43m
    $200–891

  5. Bus via Brentwood

    1. Take the bus from TA Travel Center - Seymour to Tornado Bus Co - Nashvillebus bus
    2. Take the bus from Nashville, TN to New York, NYbus bus Ny
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    37h 37m
    $304–454

Indianapolis (IND) to Mcghee Tyson Airport (TYS) flights

Calendar144Weekly Planes
Duration4h 43mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Knoxville.ExpandLaunch map view
  • Distance: 364.1 mi
  • Duration: 4h 33m

What companies run services between Columbus, IN, USA and Knoxville, TN, USA?

You can take a vehicle from Columbus to Knoxville via TA Travel Center - Seymour, Indianapolis, Lafayette Rd & Office Plaza Blvd, Ctc-R, Indianapolis Union Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 37h 19m.

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