There are 4 ways to get from Columbus to Cape Girardeau by car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, bus (Greyhound)
best- Drive from Columbus to Tupelocar
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Cape Girardeaubus
7h 20m$60–109Drive 320.3 mi
cheapest- Drive from Columbus to Cape Girardeaucar 320.3 mi
5h 47m$59–85Fly to Lambert–St. Louis International Airport, bus
- Fly from Golden Triangle Regional Airport (GTR) to Lambert–St. Louis International Airport (STL)plane GTR - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
9h 53m$166–643Fly to Cape Girardeau Municipal Airport
- Fly from Golden Triangle Regional Airport (GTR) to Cape Girardeau Municipal Airport (CGI)plane GTR - CGI
5h 17m$312–1,024
Golden Triangle Regional Airport (GTR) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Columbus to Cape Girardeau is to drive and bus which costs $60 - $110 and takes 7h 20m.
The fastest way to get from Columbus to Cape Girardeau is to fly which takes 5h 17m and costs $310 - $1,100.
The distance between Columbus and Cape Girardeau is 345 miles. The road distance is 322.1 miles.
It takes approximately 7h 20m to get from Columbus to Cape Girardeau, including transfers.
Yes, the driving distance between Columbus to Cape Girardeau is 322 miles. It takes approximately 5h 47m to drive from Columbus to Cape Girardeau.
There are 25+ hotels available in Cape Girardeau.
What companies run services between Columbus, MS, USA and Cape Girardeau, MO, USA?
American Airlines and Corporate Flight Management Inc fly from Golden Triangle Regional Airport (GTR) to Cape Girardeau Municipal Airport (CGI) 5 times a week.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 56m
- When
- Thursday and Sunday
- Estimated price
- $140–650
- Website
- contouraviation.com
Flights from Golden Triangle Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $250–950
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Memphis Bus Station to Cape Girardeau
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
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