There are 7 ways to get from Columbus to Chicago by plane, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Golden Triangle Regional Airport to Chicago Midway International Airport
best- Fly from Golden Triangle Regional Airport (GTR) to Chicago Midway International Airport (MDW)plane GTR - MDW
6h 51m$116–461Drive to Huntsville International Airport-Carl T Jones Field, fly to Chicago O'Hare International Airport
cheapest- Drive from Columbus to Huntsville International Airport-Carl T Jones Field (HSV)car
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Chicago O'Hare International Airport (ORD)plane HSV - ORD
6h 18m$90–395Drive, bus
- Drive from Columbus to Tupelocar
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
13h 41m$107–182Drive 645.9 mi
- Drive from Columbus to Chicagocar 645.9 mi
11h 32m$118–171Drive, bus to Birmingham–Shuttlesworth International Airport, fly to Chicago Midway International Airport
- Drive from Columbus to Embassy Suites by Hilton Tuscaloosa Alabama Dowtowncar
- Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus
- Fly from Birmingham–Shuttlesworth International Airport (BHM) to Chicago Midway International Airport (MDW)plane BHM - MDW
5h 50m$128–495Drive, bus to Birmingham–Shuttlesworth International Airport, fly to Chicago O'Hare International Airport
- Drive from Columbus to Embassy Suites by Hilton Tuscaloosa Alabama Dowtowncar
- Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus
- Fly from Birmingham–Shuttlesworth International Airport (BHM) to Chicago O'Hare International Airport (ORD)plane BHM - ORD
6h 33m$113–415Drive, bus via Champaign
- Drive from Columbus to Tupelocar
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Champaign Intermodal Trans Ctrbus
- Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus
15h 56m$142–212
Golden Triangle Regional Airport (GTR) to Chicago Midway International Airport (MDW) flights
Comparing Your Travel Options
The cheapest way to get from Columbus to Chicago is to drive and bus which costs $100 - $190 and takes 13h 41m.
The fastest way to get from Columbus to Chicago is to drive and bus and fly which takes 5h 50m and costs $120 - $500.
The distance between Columbus and Chicago is 605 miles. The road distance is 649.7 miles.
It takes approximately 6h 51m to get from Columbus to Chicago, including transfers.
Yes, the driving distance between Columbus to Chicago is 650 miles. It takes approximately 11h 32m to drive from Columbus to Chicago.
There are 1303+ hotels available in Chicago.
What companies run services between Columbus, MS, USA and Chicago, IL, USA?
Delta flies from Golden Triangle Regional Airport (GTR) to Chicago Midway International Airport (MDW) 3 times a day.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $75–410
Flights from Birmingham–Shuttlesworth International Airport to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $80–450
Flights from Birmingham–Shuttlesworth International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $65–360
Flights from Huntsville International Airport-Carl T Jones Field to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $75–410
Flights from Huntsville International Airport-Carl T Jones Field to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $75–400
- Website
- southwest.com
Flights from Birmingham–Shuttlesworth International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $70–410
Flights from Birmingham–Shuttlesworth International Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–410
- Website
- aa.com
Flights from Birmingham–Shuttlesworth International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- $55–330
Flights from Birmingham–Shuttlesworth International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $75–390
Flights from Huntsville International Airport-Carl T Jones Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- $60–350
- Website
- united.com
Flights from Birmingham–Shuttlesworth International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $55–330
Flights from Huntsville International Airport-Carl T Jones Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–26
- Website
- Greyhound
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–26
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 5 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 8h 30m
- Frequency
- 5 times a week
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Bus from Champaign Intermodal Trans Ctr to Chicago Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
- Phone
- +1 (205) 719-0469
- [email protected]
- Website
- Groome Transportation
Bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworth
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- Groome Transportation
- Schedules at
- Groome Transportation
Bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworth
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- Groome Transportation
- Schedules at
- Groome Transportation
- Phone
- +1 800-448-0572
- [email protected]
- Website
- Peoria Charter
Bus from Champaign Intermodal Trans Ctr to Chicago Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Website
- Peoria Charter
- Schedules at
- Peoria Charter Schedules
- cash
- $60
- online
- $45
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