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How to get fromColumbus to Louisvilleby plane, car, or bus

Find Transport to Louisville

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There are 6 ways to get from Columbus to Louisville by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Golden Triangle Regional Airport to Louisville International Airport

    best
    1. Fly from Golden Triangle Regional Airport (GTR) to Louisville International Airport (SDF)plane plane GTR - SDF
    5h 34m
    $135–599

  2. Drive 407.1 mi

    cheapest
    1. Drive from Columbus to Louisvillecar car 407.1 mi
    8h 11m
    $75–108

  3. Drive, bus via Nashville

    1. Drive from Columbus to Tupelocar car
    2. Take the bus from Tupelo to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    12h 30m
    $86–160

  4. Fly Golden Triangle Regional Airport to Blue Grass Airport, drive

    1. Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)plane plane GTR - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 21m
    $182–815

  5. Drive, bus to Birmingham–Shuttlesworth International Airport, fly to Louisville International Airport

    1. Drive from Columbus to Embassy Suites by Hilton Tuscaloosa Alabama Dowtowncar car
    2. Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus bus
    3. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Louisville International Airport (SDF)plane plane BHM - SDF
    8h 10m
    $152–683

  6. Drive, bus

    1. Drive from Columbus to Tupelocar car
    2. Take the bus from Tupelo to Memphis Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus
    13h 28m
    $123–264

Golden Triangle Regional Airport (GTR) to Louisville International Airport (SDF) flights

Calendar21Weekly Planes
Duration5hAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Louisville.ExpandLaunch map view
  • Distance: 382.2 mi
  • Duration: 5h 34m

What companies run services between Columbus, MS, USA and Louisville, KY, USA?

Delta and American Airlines fly from Golden Triangle Regional Airport (GTR) to Louisville International Airport (SDF) 3 times a day.

Airlines
Bus operators

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