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How to get fromColumbus to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus (Greyhound), bus, or train

Find Transport to Des Moines

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There are 5 ways to get from Columbus to Des Moines by plane, bus (Flixbus, Greyhound), car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 28m
    $159–824

  2. Bus via Indianapolis (Greyhound)

    cheapest
    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 5m
    $98–192

  3. Bus

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h
    $108–190

  4. Drive 620.1 mi

    1. Drive from Columbus to Des Moinescar car 620.1 mi
    11h 27m
    $114–164

  5. Bus, train

    1. Take the bus from Columbus - Mound St to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    17h 59m
    $171–369

Columbus to Des Moines by bus

Calendar30Weekly Buses
Duration15hAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Des Moines.ExpandLaunch map view
  • Distance: 591.9 mi
  • Duration: 5h 28m

What companies run services between Columbus, OH, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Chicago Bus Station in around 15h.

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