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How to get fromColumbus to Florida Keysby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

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There are 8 ways to get from Columbus to Florida Keys by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Key West International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Key West International Airport (EYW)plane plane CMH - EYW
    9h 13m
    $189–597

  2. Fly Rickenbacker International Airport to Key West International Airport

    cheapest
    1. Fly from Rickenbacker International Airport (LCK) to Key West International Airport (EYW)plane plane LCK - EYW
    5h 58m
    $187–510

  3. Bus

    1. Take the bus from Columbus to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    38h 35m
    $220–431

  4. Bus, train

    1. Take the bus from Columbus to Pittsburgh Intermodal Stationbus bus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    47h 32m
    $569–1,216

  5. Drive 1,288.1 mi

    1. Drive from Columbus to Florida Keyscar car 1,288.1 mi
    22h 19m
    $236–340

  6. Fly John Glenn Columbus International Airport to Miami International Airport, shuttle

    1. Fly from John Glenn Columbus International Airport (CMH) to Miami International Airport (MIA)plane plane CMH - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 52m
    $624–1,287

  7. Fly John Glenn Columbus International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from John Glenn Columbus International Airport (CMH) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CMH - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 17m
    $504–1,607

  8. Bus to Covington, fly to Key West International Airport

    1. Take the bus from Columbus to Cincinnatibus bus
    2. Fly from Covington (CVG) to Key West International Airport (EYW)plane plane CVG - EYW
    10h 7m
    $200–683

Columbus to Florida Keys by bus and foot

Calendar14Weekly Services
Duration38h 35mAverage Duration
Ticket$220Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Florida Keys.ExpandLaunch map view
  • Distance: 1,102.9 mi
  • Duration: 9h 13m

What companies run services between Columbus, OH, USA and Florida Keys, FL, USA?

American Airlines, Delta, and United Airlines fly from John Glenn Columbus International Airport (CMH) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Columbus to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 38h 35m.

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