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How to get fromColumbus to Saint Charlesby plane, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Find Transport to Saint Charles

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There are 4 ways to get from Columbus to Saint Charles by plane, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, line 34 bus

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    4h 19m
    $806–907

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    10h 53m
    $65–121

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h 35m
    $66–123

  4. Drive 430.4 mi

    1. Drive from Columbus to Saint Charlescar car 430.4 mi
    7h 17m
    $79–114

Columbus to Saint Charles by bus and train

Calendar10Weekly Services
Duration10h 35mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Saint Charles.ExpandLaunch map view
  • Distance: 435.4 mi
  • Duration: 4h 19m

What companies run services between Columbus, OH, USA and Saint Charles, MO, USA?

You can take a bus from Columbus to 4375 Rider Trail North Sb via Dayton Trotwood Bus Station, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h 35m.

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Bus operators

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