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How to get fromColumbus to Senecaby plane, taxi, bus, car, or train

Find Transport to Seneca

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There are 6 ways to get from Columbus to Seneca by plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Greenville–Spartanburg International Airport (GSP)plane plane CMH - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 14m
    $232–823

  2. Drive 460.6 mi

    cheapest
    1. Drive from Columbus to Senecacar car 460.6 mi
    10h 28m
    $85–122

  3. Bus, taxi

    1. Take the bus from Columbus - Mound St to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    3. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    14h 56m
    $210–394

  4. Fly to Asheville Regional Airport, drive

    1. Fly from John Glenn Columbus International Airport (CMH) to Asheville Regional Airport (AVL)plane plane CMH - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 14m
    $89–472

  5. Bus, train

    1. Take the bus from Columbus - Mound St to Charlotte Bus Stationbus bus Columbus
    2. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train Crescent
    14h 57m
    $134–259

  6. Bus, train via N Murray Hill Rd & Beacon Hill Rd

    1. Take the bus from Wilson & Ferrell Shell Station - Columbus to Charlotte Bus Stationbus bus Greyhound US0140
    2. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train Crescent
    18h 44m
    $143–284

John Glenn Columbus International Airport (CMH) to Greenville–Spartanburg International Airport (GSP) flights

Calendar17Weekly Planes
Duration3hAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Seneca.ExpandLaunch map view
  • Distance: 416.8 mi
  • Duration: 4h 14m

What companies run services between Columbus, OH, USA and Seneca, SC, USA?

There is no direct connection from Columbus to Seneca. However, you can take the line 7 bus to John Glenn Columbus Intnl Airport (CMH), walk to John Glenn Columbus International Airport (CMH) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Charlotte Bus Station, walk to Trade St & Graham St, take the line 34 bus to Transit Center- Bay A, walk to Transit Center- Bay O, take the line 11 bus to Tryon St & Dorton St, walk to Charlotte, take the bus to Taqueria Guadalajara - Greenville, then take the taxi to Seneca.

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