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How to get fromColumbus to Tupeloby plane, car, bus (Amtrak, Greyhound, Flixbus), bus, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 8 ways to get from Columbus to Tupelo by plane, car, bus (Amtrak, Greyhound, Flixbus), bus, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Golden Triangle Regional Airport (GTR)plane plane CMH - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    7h 16m
    $108–520

  2. Fly to Tupelo Regional Airport

    cheapest
    1. Fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP)plane plane CMH - TUP
    6h 20m
    $91–461

  3. Bus via Louisville

    1. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    15h 44m
    $107–213

  4. Drive 572.7 mi

    1. Drive from Columbus to Tupelocar car 572.7 mi
    10h 46m
    $105–151

  5. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from John Glenn Columbus International Airport (CMH) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane CMH - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    8h 7m
    $135–688

  6. Fly to Memphis, bus

    1. Fly from John Glenn Columbus International Airport (CMH) to Memphis (MEM)plane plane CMH - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    9h 19m
    $169–847

  7. Bus

    1. Take the bus from Columbus to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    17h 59m
    $118–220

  8. Bus via Atlanta (Greyhound)

    1. Take the bus from Columbus to Atlanta Bus Stationbus bus Greyhound US0105
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    24h 54m
    $151–282

John Glenn Columbus International Airport (CMH) to Golden Triangle Regional Airport (GTR) flights

Calendar22Weekly Planes
Duration5h 42mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Columbus to Tupelo.ExpandLaunch map view
  • Distance: 625.9 mi
  • Duration: 7h 16m

What companies run services between Columbus, OH, USA and Tupelo, MS, USA?

You can take a bus from Columbus - Downtown - Mound St to Tupelo via Louisville, KY, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 15h 44m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Tupelo Regional Airport (TUP) 4 times a day.

Airlines
Bus operators

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