There are 3 ways to get from Columbus, OH to St. Louis by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane CMH - STL
3h 25m$812–913Bus (Greyhound)
cheapest- Take the bus from Columbus to St Louis Bus Stationbus Greyhound US0421
9h 10m$65–110Drive 416.8 mi
- Drive from Columbus, OH to St. Louiscar 416.8 mi
7h$77–110
Columbus, OH to St. Louis by foot and bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Columbus, OH to St. Louis is to bus which costs $65 - $110 and takes 9h 10m.
The fastest way to get from Columbus, OH to St. Louis is to fly which takes 3h 25m and costs $800 - $950.
Yes, there is a direct bus departing from Columbus and arriving at St Louis Bus Station station. Services depart three times a day, and operate every day. The journey takes approximately 9h 5m.
The distance between Columbus, OH and St. Louis is 435 miles. The road distance is 419.3 miles.
The best way to get from Columbus, OH to St. Louis without a car is to bus which takes 9h 10m and costs $65 - $110.
It takes approximately 3h 25m to get from Columbus, OH to St. Louis, including transfers.
Columbus, OH to St. Louis bus services, operated by Greyhound USA, depart from Columbus station.
The best way to get from Columbus, OH to St. Louis is to fly which takes 3h 25m and costs $800 - $950. Alternatively, you can bus, which costs $65 - $110 and takes 9h 10m.
Columbus, OH to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
St. Louis is 1h behind Columbus, OH. It is currently 4:42 PM in Columbus, OH and 3:42 PM in St. Louis.
What companies run services between Columbus, OH, USA and St. Louis, MO, USA?
Southwest Airlines and Delta fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from Columbus to St Louis Bus Station 3 times a day. Tickets cost $65–110 and the journey takes 9h 5m.
- Website
- southwest.com
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $90–600
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 25m
- When
- Saturday to Friday
- Estimated price
- $100–650
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 37m
- When
- Monday to Wednesday
- Estimated price
- $110–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- 3 times a day
- Estimated price
- $65–110
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Columbus, OH to St. Louis is 419 miles. It takes approximately 7h to drive from Columbus, OH to St. Louis.
Book your Columbus, OH to St. Louis bus tickets online with Omio and FlixBus.
There are 558+ hotels available in St. Louis.