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How to get fromColumbus to St. Louisby taxi, plane, train (Amtrak), train, bus, or car

Find Transport to St. Louis

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There are 7 ways to get from Columbus to St. Louis by taxi, plane, train (Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Dane County Regional Airport-Truax Field, fly

    best
    1. Take the taxi from Columbus to Madison-Airport-MSNtaxi taxi
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL)plane plane MSN - STL
    4h 59m
    $149–553

  2. Drive  368.6 mi

    cheapest
    1. Drive from Columbus to St. Louiscar car 368.6 mi
    6h 22m
    $66–95

  3. Train (Amtrak)

    1. Take the train from Columbus Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    8h 44m
    $232–367

  4. Train, bus

    1. Take the train from Columbus Amtrak Station to Milwaukeetrain train
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    10h 40m
    $100–155

  5. Train to General Mitchell International Airport, fly

    1. Take the train from Columbus Amtrak Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    4h 47m
    $131–672

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Columbus Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    6h 51m
    $172–735

  7. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Columbus Amtrak Station to Glenview Amtrak Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    6h 50m
    $400–823

Columbus to St. Louis by train (Amtrak)

Calendar21Weekly Trains
Duration8h 44mAverage Duration
Ticket$232Cheapest Price
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Comparing Your Travel Options

Map of how to get from Columbus to St. Louis.ExpandLaunch map view
  • Distance: 347.2 mi
  • Duration: 4h 59m

What companies run services between Columbus, WI, USA and St. Louis, MO, USA?

You can take a train from Columbus Amtrak Station to St. Louis via Chicago Union Station in around 8h 44m.

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