There are 11 ways to get from Como to Isernia by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S. Giovanni to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
7h 9m€104–182Fly Milano Malpensa Airport to Naples Airport, train
cheapest- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Caserta to Iserniatrain
7h 23m€35–177Bus
- Take the bus from Como to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
8h 42m€89–121Drive 773.7 km
- Drive from Como to Iserniacar 773.7 km
7h 19m€126–181Bus via Florence
- Take the bus from Como to Florence Villa Constanza Bus Stationbus 518
- Take the bus from Florence Villa Constanza Bus Station to Iserniabus 433
17h 5m€88–133Fly Milan Linate Airport to Fiumicino International Airport, train
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Iserniatrain
7h 32m€86–229Fly Milan Linate Airport to Naples Airport, train
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Caserta to Iserniatrain
7h 38m€73–207Fly Milano Malpensa Airport to Abruzzo Airport, bus
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 2m€38–199Train, bus to Il Caravaggio International Airport, fly to Naples Airport
- Take the train from Como S. Giovanni to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Caserta to Iserniatrain
7h 50m€79–289Train, bus to Il Caravaggio International Airport, fly to Abruzzo Airport, bus
- Take the train from Como S. Giovanni to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Abruzzo Airport (PSR)plane BGY - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 24m€64–311Fly Milano Malpensa Airport to Salerno Costa D'Amalfi Airport, train
- Fly from Milano Malpensa Airport (MXP) to Salerno Costa D'Amalfi Airport (QSR)plane MXP - QSR
- Take the train from Salerno to Casertatrain
- Take the train from Caserta to Iserniatrain
9h 30m€53–212
Como to Isernia by train
Comparing Your Travel Options
The cheapest way to get from Como to Isernia is to fly and bus which costs €35 - €200 and takes 8h 2m.
The fastest way to get from Como to Isernia is to train which takes 7h 9m and costs €100 - €190.
No, there is no direct bus from Como to Isernia. However, there are services departing from Como and arriving at Isernia via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 8h 42m.
No, there is no direct train from Como to Isernia. However, there are services departing from Como S. Giovanni and arriving at Isernia via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 9m.
The distance between Como and Isernia is 813 km. The road distance is 773.7 km.
The best way to get from Como to Isernia without a car is to train which takes 7h 9m and costs €100 - €190.
It takes approximately 7h 9m to get from Como to Isernia, including transfers.
Como to Isernia bus services, operated by Onebus, depart from Como station.
Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
The best way to get from Como to Isernia is to train which takes 7h 9m and costs €100 - €190. Alternatively, you can bus, which costs €85 - €130 and takes 8h 42m.
What companies run services between Como, Italy and Isernia, Italy?
You can take a train from Como S. Giovanni to Isernia via Milano Centrale and Roma Termini in around 7h 9m. Alternatively, you can take a bus from Como to Isernia via Casello - A1 Ingresso Caianello in around 8h 42m.
- Website
- ita-airways.com
Flights from Milan Linate Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €55–180
Flights from Milan Linate Airport to Naples Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €55–160
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Saturday
- Estimated price
- €26–170
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €23–170
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Saturday and Monday
- Estimated price
- €45–200
Flights from Il Caravaggio International Airport to Abruzzo Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Saturday, Sunday, and Friday
- Estimated price
- €40–230
- Website
- easyjet.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Saturday
- Estimated price
- €35–160
Flights from Milano Malpensa Airport to Salerno Costa D'Amalfi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- €45–250
- Website
- aeroitalia.com
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €130–220
Flights from Milano Malpensa Airport to Salerno Costa D'Amalfi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €30–170
- Website
- flyulendo.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €13–140
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €17–27
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €17–27
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €17–27
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Salerno to Caserta
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Salerno to Caserta
- Ave. Duration
- 40 min
- Frequency
- 4 times a week
- Estimated price
- €6–13
- Website
- Trenitalia Intercity
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Como to Casello - A1 Ingresso Caianello
- Ave. Duration
- 6h 47m
- Frequency
- Once a week
- Estimated price
- €85–120
- Website
- Onebus
- Phone
- 0865.221788
- [email protected]
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Bus from Pescara Airport to San Salvo Marina
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
Bus from Pescara Airport to San Salvo Marina
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Como to Florence Villa Constanza Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Isernia
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from San Salvo Marina to Isernia
- Ave. Duration
- 1h 12m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
Bus from San Salvo Marina to Isernia
- Ave. Duration
- 1h 12m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
- [email protected]
- Website
- TERRAVISION
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–23
- Website
- TERRAVISION
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–23
- Website
- TERRAVISION
- Phone
- 035.319366
- [email protected]
- Website
- orioshuttle.com
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–15
- Schedules at
- orioshuttle.com
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–15
- Schedules at
- orioshuttle.com
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Booking & Getting There
Como to Isernia bus services, operated by Onebus, arrive at Casello - A1 Ingresso Caianello station.
Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Como to Isernia is 774 km. It takes approximately 7h 19m to drive from Como to Isernia.
Book your Como to Isernia train tickets online with Omio.
Book your Como to Isernia bus tickets online with Omio.
There are 461+ hotels available in Isernia.





































