There are 11 ways to get from Como to Isernia by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S. Giovanni to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Iserniatrain Re
7h 16m€110–257Fly Milano Malpensa Airport to Naples Airport, train
cheapest- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Caserta to Iserniatrain
7h 23m€34–180Bus
- Take the bus from Como to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
8h 42m€89–121Drive 773.7 km
- Drive from Como to Iserniacar 773.7 km
7h 19m€122–176Bus via Rome
- Take the bus from Como to Roma, Autostazione Tiburtinabus 518
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
12h 50m€57–99Fly Milan Linate Airport to Naples Airport, train
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Caserta to Iserniatrain
7h 38m€68–210Fly Milan Linate Airport to Fiumicino International Airport, train
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Iserniatrain
7h 32m€82–235Fly Milan Linate Airport to Foggia Gino Lisa Airport, bus
- Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane LIN - FOG
- Take the bus from Foggia to Iserniabus
7h 53m€92–319Train, bus to Il Caravaggio International Airport, fly to Naples Airport
- Take the train from Como S. Giovanni to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Caserta to Iserniatrain
7h 57m€74–304Fly Milano Malpensa Airport to Abruzzo Airport, bus
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara to Iserniabus
8h 28m€42–208Fly Milano Malpensa Airport to Salerno Costa D'Amalfi Airport, train
- Fly from Milano Malpensa Airport (MXP) to Salerno Costa D'Amalfi Airport (QSR)plane MXP - QSR
- Take the train from Salerno to Casertatrain
- Take the train from Caserta to Iserniatrain
9h 35m€54–216
Como to Isernia by train
Questions & Answers
The cheapest way to get from Como to Isernia is to bus via Rome which costs €55 - €100 and takes 12h 50m.
The fastest way to get from Como to Isernia is to train which takes 7h 16m and costs €110 - €260.
No, there is no direct bus from Como to Isernia. However, there are services departing from Como and arriving at Isernia via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 8h 42m.
No, there is no direct train from Como to Isernia. However, there are services departing from Como S. Giovanni and arriving at Isernia via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 16m.
The distance between Como and Isernia is 794 km. The road distance is 773.7 km.
The best way to get from Como to Isernia without a car is to train which takes 7h 16m and costs €110 - €260.
It takes approximately 7h 16m to get from Como to Isernia, including transfers.
Como to Isernia bus services, operated by Onebus, depart from Como station.
Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
The best way to get from Como to Isernia is to train which takes 7h 16m and costs €110 - €260. Alternatively, you can bus, which costs €85 - €130 and takes 8h 42m.
What companies run services between Como, Italy and Isernia, Italy?
You can take a train from Como S. Giovanni to Isernia via Milano Centrale and Roma Termini in around 7h 16m. Alternatively, you can take a bus from Como to Isernia via Casello - A1 Ingresso Caianello in around 8h 42m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €30–140
Flights from Milano Malpensa Airport to Naples Airport via Alghero
- Ave. Duration
- 3h 45m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €30–140
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–200
Flights from Il Caravaggio International Airport to Naples Airport via Palermo
- Ave. Duration
- 3h 40m
- When
- Tuesday
- Estimated price
- €40–200
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €27–180
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €16–50
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €16–50
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Como to Casello - A1 Ingresso Caianello
- Ave. Duration
- 6h 47m
- Frequency
- Once a week
- Estimated price
- €85–120
- Website
- Onebus
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More Questions & Answers
Como to Isernia bus services, operated by Onebus, arrive at Casello - A1 Ingresso Caianello station.
Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Como to Isernia is 774 km. It takes approximately 7h 19m to drive from Como to Isernia.
Book your Como to Isernia train tickets online with Omio.
Book your Como to Isernia bus tickets online with Omio.
There are 467+ hotels available in Isernia.



