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How to get fromCosta Mesa to Fresnoby train, bus, car, plane, bus (Greyhound, Flixbus), bus (Amtrak), or bus (Flixbus)

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There are 9 ways to get from Costa Mesa to Fresno by train, bus, car, plane, bus (Greyhound, Flixbus), bus (Amtrak), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the bus from Los Angeles - Pacoima to Fresno, CAbus bus Nogales
    8h 11m
    $90–128

  2. Drive  256.9 mi

    cheapest
    1. Drive from Costa Mesa to Fresnocar car 256.9 mi
    4h 24m
    $43–62

  3. Fly from John Wayne Airport Orange County

    1. Fly from John Wayne Airport Orange County (SNA) to Fresno Yosemite International Airport (FAT)plane plane SNA - FAT
    5h 59m
    $53–313

  4. Line 43 bus, bus

    1. Take the bus from Park-19Th to Fullerton Trans Ctr Dock 2bus bus 43
    2. Take the bus from Los Angeles Union Station to Fresno Bus Stationbus bus Greyhound US0810 / ...
    8h 42m
    $44–73

  5. Line 43 bus, bus via Harbor-Bernard

    1. Take the bus from Harbor-Bernard to Fullerton Trans Ctr Dock 2bus bus 43
    2. Take the bus from Los Angeles to Fresnobus bus Amtrak Thruway Connecting Service
    8h 47m

  6. Line 43 bus, bus via Los Angeles

    1. Take the bus from Park-19Th to Fullerton Trans Ctr Dock 2bus bus 43
    2. Take the bus from Los Angeles Downtown to Fresno Bus Stationbus bus FlixBus 2006 / ...
    8h 47m
    $44–68

  7. Bus

    1. Take the bus from Huntington Park to Fresno, CAbus bus Nogales / ...
    9h 14m
    $45–66

  8. Line 43 bus, train to Los Angeles International Airport, fly

    1. Take the bus from Harbor-Bernard to Fullerton Trans Ctr Dock 2bus bus
    2. Take the train from Fullerton to L.A. Union Stationtrain train
    3. Fly from Los Angeles International Airport (LAX) to Fresno Yosemite International Airport (FAT)plane plane LAX - FAT
    7h 15m
    $427–677

  9. Line 55 bus, train to San Diego International Airport, fly

    1. Take the bus from Harbor-Bernard to Flower-6Thbus bus
    2. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    3. Fly from San Diego International Airport (SAN) to Fresno Yosemite International Airport (FAT)plane plane SAN - FAT
    8h 3m
    $130–300

Costa Mesa to Fresno by bus and train

Calendar34Weekly Services
Duration8h 42mAverage Duration
Ticket$44Cheapest Price
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Comparing Your Travel Options

Map of how to get from Costa Mesa to Fresno.ExpandLaunch map view
  • Distance: 272.9 mi
  • Duration: 8h 11m

What companies run services between Costa Mesa, CA, USA and Fresno, CA, USA?

Southwest Airlines, United Airlines, and three other airlines fly from John Wayne Airport Orange County (SNA) to Fresno Yosemite International Airport (FAT) hourly. Alternatively, you can take a bus from Park-19Th to Fresno Bus Station via Fullerton Trans Ctr Dock 2, Fullerton, L.A. Union Station, and Los Angeles Union Station in around 8h 42m.

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Want to know more about travelling around United States

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