There are 5 ways to get from Costa Mesa to La Mesa by train (Amtrak), bus (Greyhound, Flixbus), car, bus (Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Irvine to San Diego Old Town Transportation Centertrain Pacific Surfliner
3h 36m$29–71Drive 86.9 mi
cheapest- Drive from Costa Mesa to La Mesacar 86.9 mi
1h 43m$16–23Bus, line 10 bus
- Take the bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stopbus Greyhound US0831
- Take the bus from Old Town Transit Center to University Av & College Avbus 10
4h 44m$19–37Line 55 bus, bus
- Take the bus from Harbor-Bernard to Flower-6Thbus 55
- Take the bus from Santa Ana to San Diegobus Los Angeles
4h 50m$24–47Line 55 bus, train
- Take the bus from Harbor-Bernard to Flower-6Thbus 55
- Take the train from Santa Ana to San Diegotrain Pacific Surfliner
5h 23m$35–84
Costa Mesa to La Mesa by bus, train, and tram (Amtrak)
Questions & Answers
The cheapest way to get from Costa Mesa to La Mesa is to drive which costs $15 - $23 and takes 1h 43m.
The fastest way to get from Costa Mesa to La Mesa is to drive which takes 1h 43m and costs $15 - $23.
No, there is no direct bus from Costa Mesa to La Mesa. However, there are services departing from Oc Fair-Yellow Gate and arriving at University Av & Allison Av via Santa Ana Bus Stop, Old Town Transit Center and University Av & College Av. The journey, including transfers, takes approximately 4h 44m.
No, there is no direct train from Costa Mesa to La Mesa station. However, there are services departing from Irvine and arriving at 70th Street Station via Old Town Station. The journey, including transfers, takes approximately 3h 36m.
The distance between Costa Mesa and La Mesa is 102 miles. The road distance is 87.4 miles.
The best way to get from Costa Mesa to La Mesa without a car is to train which takes 3h 36m and costs $29 - $75.
It takes approximately 3h 36m to get from Costa Mesa to La Mesa, including transfers.
Costa Mesa to La Mesa bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Costa Mesa to La Mesa train services, operated by Amtrak, depart from Irvine station.
The best way to get from Costa Mesa to La Mesa is to train which takes 3h 36m and costs $29 - $75. Alternatively, you can bus and line 10 bus, which costs $19 - $40 and takes 4h 44m.
What companies run services between Costa Mesa, CA, USA and La Mesa, CA, USA?
Amtrak operates a train from Irvine to San Diego Old Town Transportation Center hourly. Tickets cost $25–55 and the journey takes 1h 40m. Alternatively, you can take a bus from Oc Fair-Yellow Gate to University Av & Allison Av via The Depot At Santa Ana Dock 9, Santa Ana Bus Stop, San Diego Greyhound Bus Stop, Old Town Transit Center, and University Av & College Av in around 4h 44m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Irvine to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Website
- Amtrak
Train from Santa Ana to San Diego
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- $29–65
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $13–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $13–23
- Schedules at
- Flixbus USA
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Old Town Transit Center to University Av & College Av
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Harbor-Bernard to Flower-6Th
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
Bus from Harbor-Bernard to Flower-6Th
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Santa Ana to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $18–29
- Schedules at
- Greyhound Mexico
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More Questions & Answers
Costa Mesa to La Mesa bus services, operated by Greyhound USA, arrive at San Diego Greyhound Bus Stop station.
Costa Mesa to La Mesa train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
Yes, the driving distance between Costa Mesa to La Mesa is 87 miles. It takes approximately 1h 43m to drive from Costa Mesa to La Mesa.
There are 2120+ hotels available in La Mesa.
















