There are 9 ways to get from Costa Mesa to Palo Alto by bus, plane, train, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 43 bus, line 76 bus to John Wayne Airport Orange County, fly to Norman Y. Mineta San José International Airport, Caltrain
best- Take the bus from Park-19Th to Harbor-Macarthurbus
- Take the bus from Macarthur-Harbor to Airport-Arrival Terminalbus
- Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane SNA - SJC
- Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain
5h 2m$201–813Bus via Los Angeles
cheapest- Take the bus from Disneyland Employee's Entrance to 6th / Los Angelesbus 460
- Take the bus from Los Angeles Downtown to San Josebus Guadalajara
15h 59m$50–79Bus
- Take the bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwichbus Westminster
11h 35m$51–69Train (Amtrak)
- Take the train from Santa Ana to Los Angelestrain Pacific Surfliner
- Take the train from Los Angeles to San Josetrain Coast Starlight
13h 44m$148–312Drive 393.5 mi
- Drive from Costa Mesa to Palo Altocar 393.5 mi
6h 45m$72–104Line 43 bus, line 76 bus to John Wayne Airport Orange County, fly to San Francisco International Airport, Caltrain
- Take the bus from Park-19Th to Harbor-Macarthurbus
- Take the bus from Macarthur-Harbor to Airport-Arrival Terminalbus
- Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane SNA - SFO
- Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain
5h 15m$197–722Line 662 bus, train to Los Angeles International Airport, fly to Norman Y. Mineta San José International Airport, Caltrain
- Take the bus from Oc Fair-Yellow Gate to The Depot At Santa Ana Dock 9bus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Norman Y. Mineta San José International Airport (SJC)plane LAX - SJC
- Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain
6h 18m$127–647Line 1 bus to Long Beach Airport, fly to Norman Y. Mineta San José International Airport
- Take the bus from Newport Trans Ctr Dock 5 to 7Th-Channelbus
- Fly from Long Beach Airport (LGB) to Norman Y. Mineta San José International Airport (SJC)plane LGB - SJC
6h 53m$65–347Fly John Wayne Airport Orange County to Oakland International Airport, train
- Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane SNA - OAK
- Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain
6h 45m$261–788
Costa Mesa to Palo Alto by bus
Questions & Answers
The cheapest way to get from Costa Mesa to Palo Alto is to bus which costs $50 - $70 and takes 11h 35m.
The fastest way to get from Costa Mesa to Palo Alto is to line 43 bus and line 76 bus and fly and Caltrain which takes 5h 2m and costs $200 - $850.
No, there is no direct bus from Costa Mesa to Palo Alto. However, there are services departing from Newport-Broadway and arriving at El Camino & Churchill via 1St-Centennial, Westminster, CA - ABC Supermarket and King & Tully. The journey, including transfers, takes approximately 11h 35m.
No, there is no direct train from Costa Mesa to Palo Alto. However, there are services departing from Santa Ana and arriving at California Avenue Caltrain Northbound via Los Angeles and San Jose Diridon Caltrain Northbound. The journey, including transfers, takes approximately 13h 44m.
The distance between Costa Mesa and Palo Alto is 373 miles. The road distance is 395.8 miles.
The best way to get from Costa Mesa to Palo Alto without a car is to bus which takes 11h 35m and costs $50 - $70.
It takes approximately 5h 2m to get from Costa Mesa to Palo Alto, including transfers.
Costa Mesa to Palo Alto bus services, operated by Hoang Express, depart from Westminster, CA - ABC Supermarket station.
Costa Mesa to Palo Alto train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Costa Mesa to Palo Alto is to bus which takes 11h 35m and costs $50 - $70. Alternatively, you can train, which costs $140 - $320 and takes 13h 44m.
What companies run services between Costa Mesa, CA, USA and Palo Alto, CA, USA?
Hoang Express operates a bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich once daily. Tickets cost $45–60 and the journey takes 6h 45m. Xe Do Hoang Transportation also services this route once daily. Alternatively, you can take a bus from Oc Fair-Yellow Gate to California Avenue Caltrain Northbound via The Depot At Santa Ana Dock 9, Santa Ana, Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 13h 44m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $50–340
Flights from John Wayne Airport Orange County to San Francisco International Airport via Las Vegas
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–270
Flights from Los Angeles International Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $45–300
Flights from Long Beach Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $50–330
Flights from John Wayne Airport Orange County to Oakland International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $55–360
- Website
- alaskaair.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $100–320
- Website
- united.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–230
- Website
- delta.com
Flights from Los Angeles International Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $45–300
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–290
Flights from Los Angeles International Airport to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 18m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–270
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northbound
- Ave. Duration
- 18 min
- Frequency
- Every 30 minutes
- Estimated price
- $4–6
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $4–6
Train from Millbrae Caltrain Southbound to California Avenue Caltrain Southbound
- Ave. Duration
- 31 min
- Frequency
- Every 30 minutes
- Estimated price
- $5–7
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $5–7
Train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northbound
- Ave. Duration
- 18 min
- Frequency
- Every 30 minutes
- Estimated price
- $4–6
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $4–6
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtrak
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $11–25
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Park-19Th to Harbor-Macarthur
- Ave. Duration
- 23 min
- Frequency
- Every 30 minutes
- Estimated price
- $2
- Schedules at
- octa.net
Bus from Macarthur-Harbor to Airport-Arrival Terminal
- Ave. Duration
- 19 min
- Frequency
- Every 3 hours
- Estimated price
- $1–2
- Schedules at
- octa.net
Bus from Park-19Th to Harbor-Macarthur
- Ave. Duration
- 23 min
- Frequency
- Every 30 minutes
- Estimated price
- $2
- Schedules at
- octa.net
Bus from Macarthur-Harbor to Airport-Arrival Terminal
- Ave. Duration
- 19 min
- Frequency
- Every 3 hours
- Estimated price
- $1–2
- Schedules at
- octa.net
Bus from Oc Fair-Yellow Gate to The Depot At Santa Ana Dock 9
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $2
- Schedules at
- octa.net
Bus from Newport Trans Ctr Dock 5 to 7Th-Channel
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $45–60
- Book at
- https://www.gotobus.com/hoangexpress/
- Website
- https://xedohoang.com/en
- Adult One-way
- $45–60
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $48–52
- Schedules at
- xedohoang.com
- Phone
- +1-323-466-3876
- [email protected]
- Website
- metro.net
Bus from Disneyland Employee's Entrance to 6th / Los Angeles
- Ave. Duration
- 1h 59m
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Website
- https://www.metro.net
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Los Angeles Downtown to San Jose
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $45–70
- Titanium
- $50–65
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More Questions & Answers
Costa Mesa to Palo Alto bus services, operated by Hoang Express, arrive at San Jose, CA - Huong Lan Sandwich station.
Costa Mesa to Palo Alto train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Costa Mesa to Palo Alto is 396 miles. It takes approximately 6h 45m to drive from Costa Mesa to Palo Alto.
There are 498+ hotels available in Palo Alto.


















