There are 5 ways to get from Costa Mesa to San Luis Obispo by train (Amtrak), bus (Flixbus), car, bus, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Santa Ana to San Luis Obispotrain Pacific Surfliner
7h 53m$82–172Line 43 bus, bus
cheapest- Take the bus from Park-19Th to Fullerton Trans Ctr Dock 2bus 43
- Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus FlixBus 2005
8h 19m$39–64Drive 224.7 mi
- Drive from Costa Mesa to San Luis Obispocar 224.7 mi
4h 9m$41–60Line 662 bus, train to Los Angeles International Airport, fly
- Take the bus from Oc Fair-Yellow Gate to The Depot At Santa Ana Dock 9bus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to San Luis Obispo County Regional Airport (SBP)plane LAX - SBP
6h 14m$240–480Train to San Diego International Airport, fly
- Take the train from Irvine to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane SAN - SBP
6h 50m$197–409
Costa Mesa to San Luis Obispo by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Costa Mesa to San Luis Obispo is to line 43 bus and bus which costs $35 - $65 and takes 8h 19m.
The fastest way to get from Costa Mesa to San Luis Obispo is to drive which takes 4h 9m and costs $40 - $60.
No, there is no direct bus from Costa Mesa to San Luis Obispo. However, there are services departing from Park-19Th and arriving at San Luis Obispo Railroad Museum via Fullerton Amtrak Station and Los Angeles Union Station. The journey, including transfers, takes approximately 8h 19m.
No, there is no direct train from Costa Mesa to San Luis Obispo. However, there are services departing from Santa Ana and arriving at San Luis Obispo via . The journey, including transfers, takes approximately 7h 53m.
The distance between Costa Mesa and San Luis Obispo is 266 miles. The road distance is 226 miles.
The best way to get from Costa Mesa to San Luis Obispo without a car is to train which takes 7h 53m and costs $80 - $180.
It takes approximately 7h 53m to get from Costa Mesa to San Luis Obispo, including transfers.
Costa Mesa to San Luis Obispo bus services, operated by OCTA, depart from Park-19Th station.
Costa Mesa to San Luis Obispo train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Costa Mesa to San Luis Obispo is to train which takes 7h 53m and costs $80 - $180. Alternatively, you can line 43 bus and bus, which costs $35 - $65 and takes 8h 19m.
What companies run services between Costa Mesa, CA, USA and San Luis Obispo, CA, USA?
Amtrak operates a train from Santa Ana to San Luis Obispo twice daily. Tickets cost $80–170 and the journey takes 6h 33m. Alternatively, you can take a bus from Park-19Th to San Luis Obispo Railroad Museum via Fullerton Trans Ctr Dock 2, Fullerton Amtrak Station, Los Angeles, and Los Angeles Union Station in around 8h 19m.
- Website
- united.com
Flights from Los Angeles International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $25–180
Flights from San Diego International Airport to San Luis Obispo County Regional Airport via Los Angeles International Airport
- Ave. Duration
- 2h 58m
- When
- Wednesday
- Estimated price
- $30–200
- Website
- alaskaair.com
Flights from San Diego International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $170–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to San Luis Obispo
- Ave. Duration
- 6h 33m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $10–23
- Website
- Amtrak
Train from Irvine to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Park-19Th to Fullerton Trans Ctr Dock 2
- Ave. Duration
- 1h 34m
- Frequency
- Every 30 minutes
- Estimated price
- $2
- Schedules at
- octa.net
Bus from Oc Fair-Yellow Gate to The Depot At Santa Ana Dock 9
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Union Station to San Luis Obispo Railroad Museum
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $29–50
- Schedules at
- Flixbus USA
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More Questions & Answers
Costa Mesa to San Luis Obispo bus services, operated by OCTA, arrive at Fullerton Trans Ctr Dock 2 station.
Costa Mesa to San Luis Obispo train services, operated by Amtrak, arrive at San Luis Obispo station.
Yes, the driving distance between Costa Mesa to San Luis Obispo is 226 miles. It takes approximately 4h 9m to drive from Costa Mesa to San Luis Obispo.
There are 273+ hotels available in San Luis Obispo.








