There are 4 ways to get from Costa Mesa to San Ysidro by bus (Greyhound), train, tram, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Santa Ana to San Ysidrobus Los Angeles
3h 40m$22–37Drive 97.1 mi
cheapest- Drive from Costa Mesa to San Ysidrocar 97.1 mi
1h 53m$18–26Train, tram
- Take the train from Irvine to San Diego Old Town Transportation Centertrain Pacific Surfliner
- Take the tram from Old Town Station to Beyer Blvd Stationtram Blue
4h 3m$29–70Line 55 bus, bus
- Take the bus from Harbor-Bernard to Flower-6Thbus 55
- Take the bus from Santa Ana Bus Stop to San Ysidro Bus Terminalbus FlixBus 2017 / ...
4h 53m$22–44
Costa Mesa to San Ysidro by bus (Greyhound)
Questions & Answers
The cheapest way to get from Costa Mesa to San Ysidro is to drive which costs $17 - $26 and takes 1h 53m.
The fastest way to get from Costa Mesa to San Ysidro is to drive which takes 1h 53m and costs $17 - $26.
No, there is no direct bus from Costa Mesa to San Ysidro. However, there are services departing from Oc Fair-Yellow Gate and arriving at San Ysidro via Santa Ana. The journey, including transfers, takes approximately 3h 40m.
No, there is no direct train from Costa Mesa to San Ysidro station. However, there are services departing from Irvine and arriving at Beyer Blvd Station via Old Town Station. The journey, including transfers, takes approximately 4h 3m.
The distance between Costa Mesa and San Ysidro is 113 miles. The road distance is 97.7 miles.
The best way to get from Costa Mesa to San Ysidro without a car is to bus which takes 3h 40m and costs $22 - $40.
It takes approximately 3h 40m to get from Costa Mesa to San Ysidro, including transfers.
Costa Mesa to San Ysidro bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Costa Mesa to San Ysidro train services, operated by Amtrak, depart from Irvine station.
Costa Mesa to San Ysidro bus services, operated by Greyhound Mexico, arrive at San Ysidro station.
What companies run services between Costa Mesa, CA, USA and San Ysidro, CA, USA?
Greyhound Mexico operates a bus from Santa Ana to San Ysidro 3 times a day. Tickets cost $20–35 and the journey takes 2h 20m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Irvine to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Tram from Old Town Station to Beyer Blvd Station
- Ave. Duration
- 53 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–13
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from Santa Ana to San Ysidro
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- greyhound.com.mx
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Harbor-Bernard to Flower-6Th
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Santa Ana Bus Stop to San Ysidro Bus Terminal
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $17–29
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Santa Ana Bus Stop to San Ysidro Bus Terminal
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $16–35
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Costa Mesa to San Ysidro train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
Yes, the driving distance between Costa Mesa to San Ysidro is 98 miles. It takes approximately 1h 53m to drive from Costa Mesa to San Ysidro.
There are 1281+ hotels available in San Ysidro.
















