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How to get fromCosta Mesa to Santa Claraby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 10 ways to get from Costa Mesa to Santa Clara by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 43 bus, line 76 bus to John Wayne Airport Orange County, fly to Norman Y. Mineta San José International Airport

    best
    1. Take the bus from Park-19Th to Harbor-Macarthurbus bus
    2. Take the bus from Macarthur-Harbor to Airport-Arrival Terminalbus bus
    3. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    4h 26m
    $197–807

  2. Bus via Los Angeles

    cheapest
    1. Take the bus from Disneyland Employee's Entrance to 6th / Los Angelesbus bus 460
    2. Take the bus from Los Angeles Downtown to San Josebus bus Guadalajara
    14h 59m
    $55–79

  3. Bus (Greyhound)

    1. Take the bus from Santa Ana Bus Stop to San Jose Diridon Stationbus bus Greyhound US0831
    9h 50m
    $60–118

  4. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    13h 23m
    $145–311

  5. Drive 380.4 mi

    1. Drive from Costa Mesa to Santa Claracar car 380.4 mi
    6h 37m
    $70–101

  6. Train to Los Angeles International Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Norman Y. Mineta San José International Airport (SJC)plane plane LAX - SJC
    5h 43m
    $132–641

  7. Fly John Wayne Airport Orange County to San Francisco International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2. Take the train from Millbrae Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    5h 36m
    $129–724

  8. Line 1 bus to Long Beach Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the bus from Newport Trans Ctr Dock 5 to 7Th-Channelbus bus
    2. Fly from Long Beach Airport (LGB) to Norman Y. Mineta San José International Airport (SJC)plane plane LGB - SJC
    6h 17m
    $61–341

  9. Fly John Wayne Airport Orange County to Oakland International Airport, train

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    6h 10m
    $227–781

  10. Train to Burbank Bob Hope Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Burbank Bob Hope Airport (BUR) to Norman Y. Mineta San José International Airport (SJC)plane plane BUR - SJC
    6h 21m
    $501–788

Costa Mesa to Santa Clara by bus and train (Greyhound)

Calendar7Weekly Services
Duration9h 50mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Costa Mesa to Santa Clara.ExpandLaunch map view
  • Distance: 357.7 mi
  • Duration: 4h 26m

What companies run services between Costa Mesa, CA, USA and Santa Clara, CA, USA?

Greyhound USA operates a bus from Santa Ana Bus Stop to San Jose Diridon Station once daily. Tickets cost $55–110 and the journey takes 8h 10m. Alternatively, you can take a bus from Oc Fair-Yellow Gate to Santa Clara Caltrain Northbound via The Depot At Santa Ana Dock 9, Santa Ana, Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 13h 23m.

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