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How to get fromCosta Mesa to Tucsonby bus, plane, train (Amtrak), car, or train

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There are 8 ways to get from Costa Mesa to Tucson by bus, plane, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 43 bus, line 76 bus to John Wayne Airport Orange County, fly to Tucson

    best
    1. Take the bus from Park-19Th to Harbor-Macarthurbus bus
    2. Take the bus from Macarthur-Harbor to Airport-Arrival Terminalbus bus
    3. Fly from John Wayne Airport Orange County (SNA) to Tucson (TUS)plane plane SNA - TUS
    5h 18m
    $84–464

  2. Bus

    cheapest
    1. Take the bus from Anaheim-Cerritos to Tucsonbus bus Cbx
    15h 14m
    $77–112

  3. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Tucson Amtrak Stationtrain train Texas Eagle / ...
    12h 46m
    $173–355

  4. Bus via Los Angeles

    1. Take the bus from Los Angeles Union Station to Tucsonbus bus FlixBus 2054
    13h 44m
    $120–174

  5. Drive 476.9 mi

    1. Drive from Costa Mesa to Tucsoncar car 476.9 mi
    7h 43m
    $87–126

  6. Line 662 bus, train to Los Angeles International Airport, fly to Tucson

    1. Take the bus from Oc Fair-Yellow Gate to The Depot At Santa Ana Dock 9bus bus
    2. Take the train from Santa Ana to Los Angelestrain train
    3. Fly from Los Angeles International Airport (LAX) to Tucson (TUS)plane plane LAX - TUS
    6h 33m
    $520–1,138

  7. Train to San Diego International Airport, fly to Tucson

    1. Take the train from Irvine to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Tucson (TUS)plane plane SAN - TUS
    6h 51m
    $467–857

  8. Fly John Wayne Airport Orange County to Phoenix, bus

    1. Fly from John Wayne Airport Orange County (SNA) to Phoenix (PHX)plane plane SNA - PHX
    2. Take the bus from Sky Harbor International Airport to University of Phoenixbus bus
    6h 46m
    $244–739

Costa Mesa to Tucson by bus and train (Amtrak)

Calendar6Weekly Services
Duration12h 46mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Costa Mesa to Tucson.ExpandLaunch map view
  • Distance: 435.5 mi
  • Duration: 5h 18m

What companies run services between Costa Mesa, CA, USA and Tucson, AZ, USA?

You can take a bus from Oc Fair-Yellow Gate to Tucson Amtrak Station via The Depot At Santa Ana Dock 9, Santa Ana, and Los Angeles in around 12h 46m. Alternatively, Jefferson Lines operates a bus from Los Angeles Union Station to Tucson once daily. Tickets cost $110–160 and the journey takes 9h 25m.

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