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How to get fromCrystal Lake to Mayo Clinicby train, plane, bus, or car

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There are 6 ways to get from Crystal Lake to Mayo Clinic by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from Crystal Lake to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    5h 20m
    $53–302

  2. Train, bus via Madison

    1. Take the train from Crystal Lake to Des Plainestrain train
    2. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    9h 56m
    $79–134

  3. Drive 294.1 mi

    1. Drive from Crystal Lake to Mayo Cliniccar car 294.1 mi
    5h 15m
    $54–78

  4. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Crystal Lake to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 55m
    $280–464

  5. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Crystal Lake to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 46m
    $135–544

  6. Train, bus

    1. Take the train from Crystal Lake to Chicago OTCtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 46m
    $106–170

Chicago O'Hare International Airport (ORD) to Rochester (RST) flights

Calendar35Weekly Planes
Duration1h 53mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Crystal Lake to Mayo Clinic.ExpandLaunch map view
  • Distance: 323.4 mi
  • Duration: 5h 20m

What companies run services between Crystal Lake, IL, USA and Mayo Clinic, MN, USA?

There is no direct connection from Crystal Lake to Mayo Clinic. However, you can take the train to Irving Park, walk to Irving Park-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Rochester (RST), walk to Rochester, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can take a train from Crystal Lake to Mayo Clinic via Des Plaines, Des Plaines Metra Station, Multi-Modal/Rental Car Facility, Madison, and Rochester in around 9h 56m.

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