Rome2Rio

Plan your Cuba Itinerary with Real Train, Bus & Inter-City Routes

Cuba travel plans with the routes already figured out

Rome2Rio itineraries for Cuba are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.

7 days in Cuba

Havana Holguín

Itinerary navigation

Day 1: Havana, Cuba

Activities
  • Visit the Museum of the Revolution
  • Visit the Great Theatre of Havana
Explore Havana itineraries
Hotel
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Days 2–3: Santiago de Cuba

Distance
Transport
Popular
Havana → Santiago de Cuba by fly
  1. Take the bus from Havana to Santiago de Cubabus bus
  2. Take the transfer from Havana to Santiago de Cubatransfer
  3. Fly from Havana to Santiago de Cubaplane plane
  4. Take the transfer from Havana to Santiago de Cubatransfer
  5. Take the bus from Havana to Santiago de Cubabus bus
3h 47m
$663–1,621
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Activities
  • San Pedro de la Roca Castle
  • Cespedes Park
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Days 4–7: Holguín, Cuba

Distance
Transport
Popular
Santiago de Cuba → Holguín by bus
  1. Take the bus from Santiago de Cuba to Holguínbus bus
3h 1m
$2–4
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Activities
  • Chorro de Maita Indigenous Village
  • Teatro Eddy Suñol
Explore Holguín itineraries
Hotel
Hotel
Recommended
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8 days in Cuba

Holguín Guantánamo

Itinerary navigation

Days 1–4: Holguín, Cuba

Activities
  • Aldea Taina
  • Playa Guardalavaca
Explore Holguín itineraries
Hotel
Hotel
Recommended
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Day 5: Havana, Cuba

Days 6–7: Santiago de Cuba

Day 8: Guantánamo, Cuba

9 days in Cuba

Santiago de Cuba Camagüey

Itinerary navigation

Days 1–2: Santiago de Cuba

Activities
  • Jardin de los Helechos
  • Museo de la Lucha Clandestina
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Day 3: Havana, Cuba

Days 4–7: Holguín, Cuba

Days 8–9: Camagüey, Cuba

Distance
Transport
Popular
Holguín → Camagüey by bus
  1. Take the bus from Holguín to Camagüeybus bus
3h 21m
$23–35
See more transport options
Activities
  • Catedral de Nuestra Senora de la Candelaria
  • Casa de la Cultura Ignacio Agramonte
Explore Camagüey itineraries
Hotel
Hotel
Recommended
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10 days in Cuba

Havana Camagüey

Itinerary navigation

Day 1: Havana, Cuba

Activities
  • Visit the Great Theatre of Havana
  • Explore Callejon de Hamel
Explore Havana itineraries
Hotel
Hotel
Recommended
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Days 2–3: Santiago de Cuba

Days 4–7: Holguín, Cuba

Distance
Transport
Popular
Santiago de Cuba → Holguín by bus
  1. Take the bus from Santiago de Cuba to Holguínbus bus
3h 1m
$2–4
See more transport options
Activities
  • Museo Provincial La Periquera
  • Jardín Botánico de Holguín
Explore Holguín itineraries
Hotel
Hotel
Recommended
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Days 8–10: Camagüey, Cuba

Distance
Transport
Popular
Holguín → Camagüey by bus
  1. Take the bus from Holguín to Camagüeybus bus
3h 21m
$23–35
See more transport options
Activities
  • Catedral de Nuestra Senora de la Candelaria
  • Iglesia de Nuestra Senora de la Merced
Explore Camagüey itineraries
Hotel
Hotel
Recommended
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11 days in Cuba

Holguín Guantánamo

Itinerary navigation

Days 1–4: Holguín, Cuba

Activities
  • Parque Calixto Garcia
  • Jardín Botánico de Holguín
Explore Holguín itineraries
Hotel
Hotel
Recommended
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Day 5: Havana, Cuba

Days 6–7: Santiago de Cuba

Days 8–11: Guantánamo, Cuba

Distance
Transport
Popular
Santiago de Cuba → Guantánamo by bus
  1. Take the bus from Santiago de Cuba to Guantánamobus bus
1h
$24–85
See more transport options
Activities
  • Galeria de Arte Regino Boti
  • Casa de la Cultura Ruben Lopez Sabariego
Explore Guantánamo itineraries
Hotel
Hotel
Recommended
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12 days in Cuba

Santiago de Cuba Guantánamo

Itinerary navigation

Days 1–2: Santiago de Cuba

Activities
  • Cespedes Park
  • Museo Emilio Bacardi Moreau
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Day 3: Havana, Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Distance
Transport
Popular
Holguín → Camagüey by bus
  1. Take the bus from Holguín to Camagüeybus bus
3h 21m
$23–35
See more transport options
Activities
  • Mercado Agropecuario
  • Casa de la Cultura Ignacio Agramonte
Explore Camagüey itineraries
Hotel
Hotel
Recommended
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Days 11–12: Guantánamo, Cuba

13 days in Cuba

Havana Guantánamo

Itinerary navigation

Day 1: Havana, Cuba

Activities
  • Visit El Morro Castle
  • Enjoy a classic car tour
Explore Havana itineraries
Hotel
Hotel
Recommended
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Days 2–3: Santiago de Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Days 11–13: Guantánamo, Cuba

14 days in Cuba

Holguín Guantánamo

Itinerary navigation

Days 1–4: Holguín, Cuba

Activities
  • Parque Las Flores
  • Aldea Taina
Explore Holguín itineraries
Hotel
Hotel
Recommended
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Day 5: Havana, Cuba

Days 6–7: Santiago de Cuba

Days 8–14: Guantánamo, Cuba

15 days in Cuba

Santiago de Cuba Guantánamo

Itinerary navigation

Days 1–2: Santiago de Cuba

Activities
  • Museo de la Lucha Clandestina
  • San Pedro de la Roca Castle
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Day 3: Havana, Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Days 11–15: Guantánamo, Cuba

16 days in Cuba

Havana Guantánamo

Itinerary navigation

Day 1: Havana, Cuba

Activities
  • Visit El Morro Castle
  • Visit Revolution Square (Plaza de la Revolución)
Explore Havana itineraries
Hotel
Hotel
Recommended
See more hotels

Days 2–3: Santiago de Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Distance
Transport
Popular
Holguín → Camagüey by bus
  1. Take the bus from Holguín to Camagüeybus bus
3h 21m
$23–35
See more transport options
Activities
  • Museo Provincial Ignacio Agramonte
  • Catedral de Nuestra Senora de la Candelaria
Explore Camagüey itineraries
Hotel
Hotel
Recommended
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Days 11–16: Guantánamo, Cuba

17 days in Cuba

Holguín Guantánamo

Itinerary navigation

Days 1–4: Holguín, Cuba

Activities
  • Cayo Saetía
  • Fábrica de Tabacos La Corona
Explore Holguín itineraries
Hotel
Hotel
Recommended
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Day 5: Havana, Cuba

Days 6–7: Santiago de Cuba

Days 8–17: Guantánamo, Cuba

18 days in Cuba

Santiago de Cuba Guantánamo

Itinerary navigation

Days 1–2: Santiago de Cuba

Activities
  • Jardin de los Helechos
  • Moncada Barracks Museum
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Day 3: Havana, Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Days 11–18: Guantánamo, Cuba

19 days in Cuba

Havana Guantánamo

Itinerary navigation

Day 1: Havana, Cuba

Activities
  • Visit Revolution Square (Plaza de la Revolución)
  • Enjoy a classic car tour
Explore Havana itineraries
Hotel
Hotel
Recommended
See more hotels

Days 2–3: Santiago de Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Days 11–19: Guantánamo, Cuba

20 days in Cuba

Holguín Guantánamo

Itinerary navigation

Days 1–4: Holguín, Cuba

Activities
  • Museo Provincial La Periquera
  • Cayo Saetía
Explore Holguín itineraries
Hotel
Hotel
Recommended
See more hotels

Day 5: Havana, Cuba

Days 6–7: Santiago de Cuba

Days 8–20: Guantánamo, Cuba

30 days in Cuba

Santiago de Cuba Guantánamo

Itinerary navigation

Days 1–2: Santiago de Cuba

Activities
  • Jardin de los Helechos
  • Santa Ifigenia Cemetery
Explore Santiago de Cuba itineraries
Hotel
Hotel
Recommended
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Day 3: Havana, Cuba

Days 4–7: Holguín, Cuba

Days 8–10: Camagüey, Cuba

Distance
Transport
Popular
Holguín → Camagüey by bus
  1. Take the bus from Holguín to Camagüeybus bus
3h 21m
$23–35
See more transport options
Activities
  • Catedral de Nuestra Senora de la Candelaria
  • Callejon de los Milagros
Explore Camagüey itineraries
Hotel
Hotel
Recommended
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Days 11–30: Guantánamo, Cuba

Popular cities in Cuba to visit