There are 6 ways to get from Cuenca, Ecuador to Santa Cruz de la Sierra by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Cuenca
best- Fly from Cuenca (CUE) to Viru Viru International Airport (VVI)plane CUE - VVI
9h 29m$249–805Bus #2
cheapest- Take the bus from Cuenca to Piurabus
- Take the bus from Piura to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Lima - Terminal Arriola to La Pazbus
- Take the bus from La Paz to Santa Cruzbus
3d 3h$149–700Bus via Iquique
- Take the bus from Terminal de Cuenca to Terminal de Piurabus
- Take the bus from Piura to Lima 28 de Juliobus
- Take the bus from Lima 28 de Julio to Tacnabus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Rodovario de Iquiquebus
- Take the bus from Iquique to Santa Cruzbus
2d 21hDrive 3,693.7 km
- Drive from Cuenca, Ecuador to Santa Cruz de la Sierracar 3,693.7 km
2d 4h$210–303Taxi to José Joaquín De Olmedo International Airport, fly
- Take the taxi from Cuenca, Ecuador to Guayaquil-Airport-GYEtaxi
- Fly from José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI)plane GYE - VVI
10h 29m$514–835Bus
- Take the bus from Terminal de Cuenca to Terminal de Piurabus
- Take the bus from Piura to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Oltursa Lima Terminal to La Pazbus
- Take the bus from La Paz to Santa Cruzbus
3d 2h$202–301
Cuenca (CUE) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Cuenca, Ecuador to Santa Cruz de la Sierra is to bus which costs $200 - $310 and takes 3 days 2h.
The fastest way to get from Cuenca, Ecuador to Santa Cruz de la Sierra is to fly which takes 9h 29m and costs $240 - $850.
No, there is no direct bus from Cuenca, Ecuador to Santa Cruz de la Sierra. However, there are services departing from Terminal de Cuenca and arriving at Santa Cruz via Piura, Lima 28 de Julio, Terminal Terrestre Internacional Manuel A. Odría, Terminal Rodoviario de Arica and Iquique. The journey, including transfers, takes approximately 2 days 21h.
The distance between Cuenca, Ecuador and Santa Cruz de la Sierra is 2404 km. The road distance is 3693.7 km.
The best way to get from Cuenca, Ecuador to Santa Cruz de la Sierra without a car is to bus via Iquique which takes 2 days 21h and costs .
It takes approximately 9h 29m to get from Cuenca, Ecuador to Santa Cruz de la Sierra, including transfers.
Cuenca, Ecuador to Santa Cruz de la Sierra bus services, operated by Super Semería, depart from Terminal de Cuenca station.
The best way to get from Cuenca, Ecuador to Santa Cruz de la Sierra is to fly which takes 9h 29m and costs $240 - $850. Alternatively, you can bus via Iquique, which costs and takes 2 days 21h.
Cuenca, Ecuador to Santa Cruz de la Sierra bus services, operated by Super Semería, arrive at Terminal de Piura station.
Santa Cruz de la Sierra is 1h ahead of Cuenca, Ecuador. It is currently 9:12 PM in Cuenca, Ecuador and 10:12 PM in Santa Cruz de la Sierra.
What companies run services between Cuenca, Ecuador and Santa Cruz de la Sierra, Bolivia?
LATAM Chile, Avianca - Aerovías del Continente Americano S.A., and Boliviana de Aviación fly from Cuenca (CUE) to Viru Viru International Airport (VVI) once daily. Alternatively, you can take a bus from Terminal de Cuenca to Santa Cruz via Terminal de Piura, Piura, Lima 28 de Julio, Tacna, Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, Terminal Rodoviario de Arica, and Iquique in around 2d 21h.
- Website
- latam.com
Flights from Cuenca to Viru Viru International Airport via Quito, Lima
- Ave. Duration
- 9h 30m
- When
- Wednesday
- Estimated price
- $240–850
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 6h 50m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–700
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Santiago
- Ave. Duration
- 13h 18m
- When
- Tuesday
- Estimated price
- $330–1,000
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Quito, Lima
- Ave. Duration
- 9h 3m
- When
- Sunday
- Estimated price
- $220–750
- Website
- avianca.com
Flights from Cuenca to Viru Viru International Airport via Quito, Bogota
- Ave. Duration
- 11h 59m
- When
- Monday, Wednesday, Thursday, Sunday, and Tuesday
- Estimated price
- $310–1,100
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Bogota
- Ave. Duration
- 9h 45m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $290–1,100
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Medellin Jose Marie Cordova, Bogota
- Ave. Duration
- 11h 50m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $300–1,100
- Website
- copaair.com
Flights from José Joaquín De Olmedo International Airport to Viru Viru International Airport via Panama City
- Ave. Duration
- 8h 42m
- When
- Every day
- Estimated price
- $200–800
- Website
- boa.bo
Flights from Cuenca to Viru Viru International Airport via Quito, Lima
- Ave. Duration
- 8h 59m
- When
- Monday
- Estimated price
- $270–800
- Phone
- +593 98 453 6454
- [email protected]
- Website
- facebook.com
Bus from Terminal de Cuenca to Terminal de Piura
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $35–38
- Book at
- redbus.pe
Bus from Terminal de Cuenca to Terminal de Piura
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $35–38
- Book at
- redbus.pe
- Phone
- +51 511 418 1111
- [email protected]
- Website
- CIVA
Bus from Piura to Lima 28 de Julio
- Ave. Duration
- 14h 24m
- Frequency
- Hourly
- Estimated price
- $35–55
- Schedules at
- CIVA
Bus from Lima 28 de Julio to Tacna
- Ave. Duration
- 20h 40m
- Frequency
- Every 4 hours
- Estimated price
- $40–55
- Schedules at
- CIVA
Bus from Piura to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 13h 45m
- Frequency
- Hourly
- Estimated price
- $35–55
- Schedules at
- CIVA
- Phone
- +51 1 4800725
- [email protected]
- Website
- floreshnos.pe
Bus from Lima 28 de Julio to Tacna
- Ave. Duration
- 22h
- Frequency
- 5 times a day
- Estimated price
- $29–45
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe
Bus from Piura to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 15h 15m
- Frequency
- 3 times a day
- Estimated price
- $23–40
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe
- Phone
- +51904244509
- [email protected]
- Website
- aeroexpreso.com.pe
Bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Arica
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $3–26
- Schedules at
- aeroexpreso.com.pe
- Book at
- aeroexpreso.com.pe
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Rodoviario de Arica to Rodovario de Iquique
- Ave. Duration
- 4h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $18–35
- [email protected]
- Website
- Pullman San Andres
Bus from Terminal Rodoviario de Arica to Rodovario de Iquique
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–45
- Schedules at
- Pullman San Andres
- Semi Cama
- $30–40
- Cama
- $30–45
- Phone
- +56 2 2570 8687
- [email protected]
- Website
- Buses Tarapaca
Bus from Terminal Rodoviario de Arica to Rodovario de Iquique
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $14–22
- Schedules at
- Buses Tarapaca
- Salon Cama
- $14–20
- Premium
- $16–22
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal Rodoviario de Arica to Rodovario de Iquique
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Book at
- Recorrido Pluss Chile
- Semi Cama
- $11–15
- Cama
- $15–22
- Phone
- +56 57 226 9210
- [email protected]
- Website
- Ramos Cholele
Bus from Terminal Rodoviario de Arica to Rodovario de Iquique
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $10–47
- Schedules at
- Ramos Cholele
- Semi cama
- $10–14
- Salón cama
- $43–47
- Phone
- +591 2527 7355
- [email protected]
- Website
- Jet Nort Super Class
Bus from Iquique to Santa Cruz
- Ave. Duration
- 13h 46m
- Frequency
- 4 times a week
- Schedules at
- Jet Nort Super Class
- Phone
- +51 993 558 525
- [email protected]
- Website
- turismocavassa.com.pe
Bus from Piura to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 16h 30m
- Frequency
- 5 times a day
- Estimated price
- $27–40
- Schedules at
- turismocavassa.com.pe
Bus from Piura to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 15h
- Frequency
- Twice daily
- Estimated price
- $27–40
- Schedules at
- turismocavassa.com.pe
- Phone
- +591 2245 8945
- [email protected]
- Website
- vicuna-travel.com
Bus from Oltursa Lima Terminal to La Paz
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $103
- Schedules at
- ticketsbolivia.com.bo
- Book at
- ticketsbolivia.com.bo
- Phone
- +591-72233555
- [email protected]
- Website
- Trans Copacabana SA
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- Trans Copacabana SA
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- Trans Copacabana SA
- Phone
- +591 71861725
- Website
- Expreso del Sur
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Expreso del Sur
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Expreso del Sur
- Phone
- +591 69414917
- Website
- Flota Bolivar
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–20
- Schedules at
- Flota Bolivar
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–20
- Schedules at
- Flota Bolivar
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
- Phone
- +591 69416892
- [email protected]
- Website
- Cosmos
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- Cosmos
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- Cosmos
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
- Phone
- +593-07 2823163
- [email protected]
- Website
- transportesazuay.com
Bus from Cuenca to Piura
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $18–40
- Schedules at
- transportesazuay.com
- Phone
- +51 994 656 518
- [email protected]
- Website
- Oltursa
Bus from Piura to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 16h
- Frequency
- Every 30 minutes
- Estimated price
- $29–45
- Website
- Oltursa
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Lima - Terminal Arriola to La Paz
- Ave. Duration
- 29h
- Frequency
- Once daily
- Estimated price
- $100–550
- Book at
- Tickets Bolivia
- Ave. Duration
- 3h 8m
- Estimated price
- $110–140
Fusion radio taxi
- Phone
- +593 7-281-1111
- Website
- facebook.com
Radio Taxi Amigos
- Phone
- +593 99 849 1019
- Website
- facebook.com
Radio Taxi Express
- Phone
- +593 09 9034 2881
- Website
- instagram.com
Radio Taxi FLASH
- Phone
- +593 99 407 6453
- Website
- facebook.com
Taxi Cuenca
- Phone
- +593 653 681 442
- Website
- taxiscuenca.es
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Travelling Croatia’s Dalmatian Coast by boat, bus, car and train, How do I get from Sydney to Melbourne, and How to get from Stansted Airport into central London - to help you get the most out of your next trip.
More Questions & Answers
Yes, the driving distance between Cuenca, Ecuador to Santa Cruz de la Sierra is 3694 km. It takes approximately 2 days 4h to drive from Cuenca, Ecuador to Santa Cruz de la Sierra.
There are 731+ hotels available in Santa Cruz de la Sierra.














































