There are 7 ways to get from Cuenca to Guayaquil by train, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Adolfo Suárez Madrid–Barajas Airport, fly to José Joaquín De Olmedo International Airport
best- Take the train from Cuenca Fernando Zobel to Madrid Chamartíntrain
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to José Joaquín De Olmedo International Airport (GYE)plane MAD - GYE
15h 3m$568–1,456Train to Adolfo Suárez Madrid–Barajas Airport, fly to Cuenca, bus
cheapest- Take the train from Cuenca Fernando Zobel to Madrid Chamartíntrain
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Cuenca (CUE)plane MAD - CUE
- Take the bus from Cuenca to Terminal Terrestre de Guayaquilbus
21h 9m$318–1,016Train to Valencia Airport, fly to José Joaquín De Olmedo International Airport
- Take the train from Cuenca Fernando Zobel to Valencia Joaquin Sorollatrain
- Fly from Valencia Airport (VLC) to José Joaquín De Olmedo International Airport (GYE)plane VLC - GYE
18h 31m$383–1,264Train to Alicante-Elche Airport, fly to José Joaquín De Olmedo International Airport
- Take the train from Cuenca Fernando Zobel to Alacant/Alicante Terminaltrain
- Fly from Alicante-Elche Airport (ALC) to José Joaquín De Olmedo International Airport (GYE)plane ALC - GYE
19h 31m$367–1,289Train to Adolfo Suárez Madrid–Barajas Airport, fly to Santa Rosa Regional Airport, bus
- Take the train from Cuenca Fernando Zobel to Madrid Chamartíntrain
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Santa Rosa Regional Airport (ETR)plane MAD - ETR
- Take the bus from Machala to Terminal Terrestre de Guayaquilbus
20h 29m$406–1,297Train to Adolfo Suárez Madrid–Barajas Airport, fly to Eloy Alfaro International Airport, bus
- Take the train from Cuenca Fernando Zobel to Madrid Chamartíntrain
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Eloy Alfaro International Airport (MEC)plane MAD - MEC
- Take the bus from Manta to Terminal Terrestre de Guayaquilbus
21h 51m$775–1,271Train to Adolfo Suárez Madrid–Barajas Airport, fly to Mariscal Sucre International Airport, bus
- Take the train from Cuenca Fernando Zobel to Madrid Chamartíntrain
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Mariscal Sucre International Airport (UIO)plane MAD - UIO
- Take the bus from Quito Terminal Carcelén to Guayaquilbus
21h 7m$536–1,180
Adolfo Suárez Madrid–Barajas Airport (MAD) to José Joaquín De Olmedo International Airport (GYE) flights
Comparing Your Travel Options
The cheapest way to get from Cuenca to Guayaquil is to train and fly and bus which costs $310 - $1,100 and takes 21h 9m.
The fastest way to get from Cuenca to Guayaquil is to train and fly which takes 15h 3m and costs $550 - $1,500.
The distance between Cuenca and Guayaquil is 9216 km.
It takes approximately 15h 3m to get from Cuenca to Guayaquil, including transfers.
Guayaquil is 6h behind Cuenca. It is currently 9:11 PM in Cuenca and 3:11 PM in Guayaquil.
There are 408+ hotels available in Guayaquil.
What companies run services between Cuenca, Spain and Guayaquil, Ecuador?
There is no direct connection from Cuenca to Guayaquil. However, you can take the train to Madrid Chamartín, take the train to Madrid-Aeropuerto T4, walk to Adolfo Suárez Madrid–Barajas Airport (MAD) airport, then fly to José Joaquín De Olmedo International Airport (GYE). Alternatively, you can take the train to Valencia Joaquin Sorolla, walk to Jesús, take the line 2 subway to Àngel Guimerà, take the line 5 subway to Aeroport, walk to Valencia Airport (VLC) airport, then fly to José Joaquín De Olmedo International Airport (GYE).
- Website
- avianca.com
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 13h 41m
- When
- Every day
- Estimated price
- $650–1,300
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via Mariscal Sucre International Airport
- Ave. Duration
- 14h 35m
- When
- Sunday
- Estimated price
- $550–1,300
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via Bogota, Mariscal Sucre International Airport
- Ave. Duration
- 18h 32m
- When
- Every day
- Estimated price
- $390–1,200
Flights from Adolfo Suárez Madrid–Barajas Airport to Eloy Alfaro International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 16h 45m
- When
- Tuesday and Saturday
- Estimated price
- $340–1,100
Flights from Adolfo Suárez Madrid–Barajas Airport to Eloy Alfaro International Airport via Bogota, Mariscal Sucre International Airport
- Ave. Duration
- 18h 11m
- When
- Every day
- Estimated price
- $420–1,300
Flights from Adolfo Suárez Madrid–Barajas Airport to Mariscal Sucre International Airport via Bogota
- Ave. Duration
- 13h 35m
- When
- Every day
- Estimated price
- $430–1,300
- Website
- latam.com
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 11h 55m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $320–1,100
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 13h 1m
- When
- Monday
- Estimated price
- $320–1,100
Flights from Valencia Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 15h
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $360–1,200
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via Mariscal Sucre International Airport
- Ave. Duration
- 13h 56m
- When
- Thursday and Saturday
- Estimated price
- $290–1,300
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via José Joaquín De Olmedo International Airport
- Ave. Duration
- 14h 4m
- When
- Monday, Wednesday, and Sunday
- Estimated price
- $320–1,000
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via Bogota, Mariscal Sucre International Airport
- Ave. Duration
- 19h 23m
- When
- Tuesday
- Estimated price
- $290–950
Flights from Adolfo Suárez Madrid–Barajas Airport to Eloy Alfaro International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 14h 24m
- When
- Wednesday, Thursday, and Sunday
- Estimated price
- $310–1,400
Flights from Adolfo Suárez Madrid–Barajas Airport to Eloy Alfaro International Airport via José Joaquín De Olmedo International Airport, Mariscal Sucre International Airport
- Ave. Duration
- 15h 24m
- When
- Wednesday
- Estimated price
- $360–1,100
Flights from Adolfo Suárez Madrid–Barajas Airport to Mariscal Sucre International Airport
- Ave. Duration
- 11h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $310–1,100
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 11h 55m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $320–1,100
Flights from Valencia Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 15h
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $360–1,200
Flights from Valencia Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport, Mariscal Sucre International Airport
- Ave. Duration
- 18h 3m
- When
- Thursday
- Estimated price
- $360–1,200
Flights from Alicante-Elche Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 15h 30m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $340–1,200
Flights from Alicante-Elche Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport, Mariscal Sucre International Airport
- Ave. Duration
- 15h 33m
- When
- Thursday
- Estimated price
- $340–1,200
Flights from Adolfo Suárez Madrid–Barajas Airport to Cuenca via Mariscal Sucre International Airport
- Ave. Duration
- 13h 24m
- When
- Thursday
- Estimated price
- $290–950
Flights from Adolfo Suárez Madrid–Barajas Airport to Eloy Alfaro International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 14h 14m
- When
- Wednesday and Thursday
- Estimated price
- $310–1,100
Flights from Adolfo Suárez Madrid–Barajas Airport to Mariscal Sucre International Airport
- Ave. Duration
- 11h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $310–1,100
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 11h 35m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $500–1,300
Flights from Alicante-Elche Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 15h 50m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $380–1,200
Flights from Adolfo Suárez Madrid–Barajas Airport to Santa Rosa Regional Airport via Mariscal Sucre International Airport
- Ave. Duration
- 13h 32m
- When
- Sunday, Monday, and Wednesday
- Estimated price
- $360–1,600
Flights from Adolfo Suárez Madrid–Barajas Airport to Mariscal Sucre International Airport
- Ave. Duration
- 10h 32m
- When
- Saturday and Sunday
- Estimated price
- $600–1,400
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 11h 35m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $500–1,300
Flights from Valencia Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 16h 45m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $400–1,200
Flights from Alicante-Elche Airport to José Joaquín De Olmedo International Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 16h 12m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $380–1,200
Flights from Adolfo Suárez Madrid–Barajas Airport to Mariscal Sucre International Airport
- Ave. Duration
- 11h 10m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $340–1,100
- Website
- copaair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to José Joaquín De Olmedo International Airport via Panama City
- Ave. Duration
- 14h 27m
- When
- Every day
- Estimated price
- $500–1,300
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Valencia Joaquin Sorolla
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $30–60
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Alacant/Alicante Terminal
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- $45–85
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Renfe AVE
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Renfe AVE
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $27–40
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Valencia Joaquin Sorolla
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- $28–45
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Alacant/Alicante Terminal
- Ave. Duration
- 1h 48m
- Frequency
- Every 3 hours
- Estimated price
- $40–65
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $27–40
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $27–40
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $27–40
- Website
- Renfe Viajeros
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $27–40
- Website
- Renfe Viajeros
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Valencia Joaquin Sorolla
- Ave. Duration
- 54 min
- Frequency
- 4 times a day
- Estimated price
- $17–30
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Alacant/Alicante Terminal
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $26–45
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Website
- Ouigo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Website
- Ouigo
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Iryo
Train from Cuenca Fernando Zobel to Valencia Joaquin Sorolla
- Ave. Duration
- 56 min
- Frequency
- 5 times a day
- Estimated price
- $20–40
- Website
- Iryo
Train from Cuenca Fernando Zobel to Alacant/Alicante Terminal
- Ave. Duration
- 1h 21m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Iryo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Iryo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Iryo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Iryo
Train from Cuenca Fernando Zobel to Madrid Chamartín
- Ave. Duration
- 1h 3m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Iryo
Bus from Machala to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $8
- Website
- Cooperativa International Ecuatoriano Pullman
- Phone
- +593 95 874 8163
- [email protected]
- Website
- Cooperativa de Transporte CIFA
Bus from Machala to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $7–15
- Schedules at
- Cooperativa de Transporte CIFA
- Phone
- +593 98 731 4698
- [email protected]
Bus from Cuenca to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $10
- Schedules at
- facebook.com
- [email protected]
- Website
- Cooperativa Reina del Camino
Bus from Manta to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Cooperativa Reina del Camino
- Phone
- +593 96 297 2979
- [email protected]
- Website
- Trans Esmeraldas S.A.
Bus from Quito Terminal Carcelén to Guayaquil
- Ave. Duration
- 5h 34m
- Frequency
- Twice daily
- Estimated price
- $16–22
- Schedules at
- Trans Esmeraldas S.A.
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