There are 5 ways to get from Cusco to Antofagasta by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF)plane CUZ - ANF
4h 48m$199–389Bus
cheapest- Take the bus from Cusco Bus Station to Tacna Bus Stationbus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal de Buses Cardenal Carlos Oviedo Cavadabus
29h 56m$48–128Bus, train
- Take the bus from Cusco to Arequipabus
- Take the bus from Arequipa to Tacnabus
- Take the train from Tacna to Aricatrain
- Take the bus from Terminal Rodoviario de Arica to Terminal de Buses Tocopillabus
- Take the bus from Terminal de Buses Tocopilla to Terminal de Buses Cardenal Carlos Oviedo Cavadabus
18h 32mDrive 1,562.5 km
- Drive from Cusco to Antofagastacar 1,562.5 km
23h 6m$235–340Bus via Oruro
- Take the bus from Cusco to Terminal de Buses La Pazbus
- Take the bus from La Paz to Patacamayabus
- Take the bus from Patacamaya to Orurobus
- Take the bus from Oruro to Terminal de Buses Cardenal Carlos Oviedo Cavadabus
30h 20m
Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF) flights
Questions & Answers
The cheapest way to get from Cusco to Antofagasta is to bus which costs $45 - $130 and takes 29h 56m.
The fastest way to get from Cusco to Antofagasta is to fly which takes 4h 48m and costs $190 - $390.
No, there is no direct bus from Cusco station to Antofagasta. However, there are services departing from Cusco Bus Station and arriving at Maipu esq. Avenida Argentina via Terminal Terrestre Internacional Manuel A. Odría, Terminal Rodoviario de Arica and Avenida Pedro Aguirre Cerda esq. Huasco. The journey, including transfers, takes approximately 29h 56m.
The distance between Cusco and Antofagasta is 1139 km. The road distance is 1562.5 km.
The best way to get from Cusco to Antofagasta without a car is to bus and train which takes 18h 32m and costs .
It takes approximately 4h 48m to get from Cusco to Antofagasta, including transfers.
Cusco to Antofagasta bus services, operated by Expreso Turismo San Martin Nobleza, depart from Cusco Bus Station.
The best way to get from Cusco to Antofagasta is to fly which takes 4h 48m and costs $190 - $390. Alternatively, you can bus, which costs $45 - $130 and takes 29h 56m.
Cusco to Antofagasta bus services, operated by Expreso Turismo San Martin Nobleza, arrive at Tacna Bus Station.
Antofagasta is 2h ahead of Cusco. It is currently 12:50 PM in Cusco and 2:50 PM in Antofagasta.
What companies run services between Cusco, Peru and Antofagasta, Chile?
LATAM Chile and JetSMART fly from Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF) once daily. Alternatively, you can take a bus from Cusco Bus Station to Maipu esq. Avenida Argentina via Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, Terminal Rodoviario de Arica, Terminal de Buses Cardenal Carlos Oviedo Cavada, and Avenida Pedro Aguirre Cerda esq. Huasco in around 29h 56m.
- Website
- latam.com
Flights from Alejandro Velasco Astete International Airport to Antofagasta Airport via Lima
- Ave. Duration
- 4h 27m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $160–370
Flights from Alejandro Velasco Astete International Airport to Antofagasta Airport via Santiago
- Ave. Duration
- 6h 23m
- When
- Wednesday
- Estimated price
- $160–370
Flights from Alejandro Velasco Astete International Airport to Antofagasta Airport via Arequipa, Lima
- Ave. Duration
- 8h 35m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $160–370
- Phone
- +51 52 611824
- Website
- Ferrocarril Tacna-Arica
Train from Tacna to Arica
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $6
- Schedules at
- Ferrocarril Tacna-Arica
- Phone
- +51 993 585 217
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
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More Questions & Answers
Yes, the driving distance between Cusco to Antofagasta is 1563 km. It takes approximately 23h 6m to drive from Cusco to Antofagasta.
There are 319+ hotels available in Antofagasta.




