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How to get fromCusco to Antofagastaby plane, bus, train, or car

Find Transport to Antofagasta

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There are 5 ways to get from Cusco to Antofagasta by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF)plane plane CUZ - ANF
    4h 48m
    $198–410

  2. Bus

    cheapest
    1. Take the bus from Cusco Bus Station to Tacna Bus Stationbus bus
    2. Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus bus
    3. Take the bus from Terminal Rodoviario de Arica to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus
    29h 56m
    $47–127

  3. Bus, train

    1. Take the bus from Cusco to Arequipabus bus
    2. Take the bus from Arequipa to Tacnabus bus
    3. Take the train from Tacna to Aricatrain train
    4. Take the bus from Terminal Rodoviario de Arica to Terminal de Buses Tocopillabus bus
    5. Take the bus from Terminal de Buses Tocopilla to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus
    18h 32m

  4. Drive  1,562.5 km

    1. Drive from Cusco to Antofagastacar car 1,562.5 km
    23h 6m
    $235–340

  5. Bus via Oruro

    1. Take the bus from Cusco to Terminal de Buses La Pazbus bus
    2. Take the bus from La Paz to Patacamayabus bus
    3. Take the bus from Patacamaya to Orurobus bus
    4. Take the bus from Oruro to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus
    30h 20m

Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF) flights

Calendar8Weekly Planes
Duration5h 59mAverage Duration
Ticket$177Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cusco to Antofagasta.ExpandLaunch map view
  • Distance: 1,138.6 km
  • Duration: 4h 48m

What companies run services between Cusco, Peru and Antofagasta, Chile?

LATAM Chile and JetSMART fly from Alejandro Velasco Astete International Airport (CUZ) to Antofagasta Airport (ANF) once daily. Alternatively, you can take a bus from Cusco Bus Station to Maipu esq. Avenida Argentina via Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, Terminal Rodoviario de Arica, Terminal de Buses Cardenal Carlos Oviedo Cavada, and Avenida Pedro Aguirre Cerda esq. Huasco in around 29h 56m.

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