There are 5 ways to get from Cusco to La Serena by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC)plane CUZ - LSC
7h 11m$130–440Bus
cheapest- Take the bus from Cusco Bus Station to Tacna Bus Stationbus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
42h 50m$85–180Bus, drive
- Take the bus from Cusco to Arequipabus
- Take the bus from Arequipa to Tacnabus
- Drive from Tacna to El Roble / Dr. Amador Neghmecar
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
33h 43mDrive 2,386.6 km
- Drive from Cusco to La Serenacar 2,386.6 km
32h 43m$359–519Bus via Arequipa
- Take the bus from Cusco to Arequipabus
- Take the bus from Arequipa to Tacnabus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
35h 55m
Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) flights
Questions & Answers
The cheapest way to get from Cusco to La Serena is to bus which costs $85 - $180 and takes 42h 50m.
The fastest way to get from Cusco to La Serena is to fly which takes 7h 11m and costs $130 - $440.
No, there is no direct bus from Cusco to La Serena. However, there are services departing from Cusco and arriving at Terminal de buses La Serena via Arequipa, Terminal Terrestre Internacional Manuel A. Odría and Terminal Rodoviario de Arica. The journey, including transfers, takes approximately 35h 55m.
The distance between Cusco and La Serena is 1823 km. The road distance is 2386.6 km.
The best way to get from Cusco to La Serena without a car is to bus via Arequipa which takes 35h 55m and costs .
It takes approximately 7h 11m to fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC), including transfers and time at the airport.
Cusco to La Serena bus services, operated by Andoriña Tours, depart from Cusco station.
The best way to get from Cusco to La Serena is to fly which takes 7h 11m and costs $130 - $440. Alternatively, you can bus via Arequipa, which costs and takes 35h 55m.
There is no direct flight from Alejandro Velasco Astete International Airport Airport to La Florida Airport Airport. The quickest flight takes 7h 11m and has one stopover.
Cusco to La Serena bus services, operated by Andoriña Tours, arrive at Arequipa station.
What companies run services between Cusco, Peru and La Serena, Chile?
LATAM Chile and Sky Airline fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) once daily. Alternatively, you can take a bus from Cusco to Terminal de buses La Serena via Arequipa, Tacna, Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, and Terminal Rodoviario de Arica in around 35h 55m.
- Website
- latam.com
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Santiago
- Ave. Duration
- 7h 11m
- When
- Tuesday
- Estimated price
- $140–550
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Lima, Santiago
- Ave. Duration
- 10h 2m
- When
- Saturday, Wednesday, Sunday, Tuesday, and Friday
- Estimated price
- $170–600
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Lima, Antofagasta
- Ave. Duration
- 10h 27m
- When
- Monday and Wednesday
- Estimated price
- $150–550
- Website
- skyairline.com
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Lima, Santiago
- Ave. Duration
- 12h 13m
- When
- Saturday
- Estimated price
- $130–440
- Phone
- +51 993 585 217
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
- Phone
- +51 953 954 708
- [email protected]
- Website
- redbus.pe
Bus from Arequipa to Tacna
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
Bus from Arequipa to Tacna
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h
- Frequency
- Every 4 hours
- Estimated price
- $74–120
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $75–100
- Cama
- $80–120
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h
- Frequency
- Every 4 hours
- Estimated price
- $74–120
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $75–100
- Cama
- $80–120
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h 20m
- Frequency
- Twice daily
- Estimated price
- $55–73
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h 20m
- Frequency
- Twice daily
- Estimated price
- $55–73
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
- Phone
- +51904244509
- [email protected]
- Website
- aeroexpreso.com.pe
Bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Arica
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $3–26
- Schedules at
- aeroexpreso.com.pe
- Book at
- aeroexpreso.com.pe
Bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Arica
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $3–26
- Schedules at
- aeroexpreso.com.pe
- Book at
- aeroexpreso.com.pe
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 22h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–85
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $35–55
- Cama
- $60–85
- Premium
- $70–85
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 22h 30m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Book at
- https://www.recorrido.cl/pluss-chile/en
- Semi Cama
- $30–45
- Cama
- $50–55
- Phone
- +56 57 226 9210
- [email protected]
- Website
- busesramoscholele.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $30–53
- Schedules at
- busesramoscholele.cl
- Semi cama
- $30–45
- Salón cama
- $48–53
- Phone
- +51 051 602 943
- Website
- facebook.com
Bus from Cusco Bus Station to Tacna Bus Station
- Ave. Duration
- 15h 30m
- Frequency
- Twice daily
- Estimated price
- $26–35
- Schedules at
- facebook.com
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More Questions & Answers
La Serena is 1h ahead of Cusco. It is currently 4:10 AM in Cusco and 5:10 AM in La Serena.
Yes, the driving distance between Cusco to La Serena is 2387 km. It takes approximately 32h 43m to drive from Cusco to La Serena.
Sky Airline and LATAM Chile offer flights from Alejandro Velasco Astete International Airport Airport to La Florida Airport Airport.
There are 1013+ hotels available in La Serena.























