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How to get fromCusco to La Serenaby plane, bus, or car

Find Transport to La Serena

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There are 5 ways to get from Cusco to La Serena by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC)plane plane CUZ - LSC
    5h 16m
    $160–550
  2. Bus

    cheapest
    1. Take the bus from Cusco Bus Station to Tacna Bus Stationbus bus
    2. Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus bus
    3. Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus bus
    42h 50m
    $79–170
  3. Bus, drive

    1. Take the bus from Cusco to Arequipabus bus
    2. Take the bus from Arequipa to Tacnabus bus
    3. Drive from Tacna to El Roble / Dr. Amador Neghmecar car
    4. Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus bus
    33h 43m
  4. Drive  2,408 km

    1. Drive from Cusco to La Serenacar car 2,408 km
    33h 57m
    $362–523
  5. Bus via Arequipa

    1. Take the bus from Cusco to Arequipabus bus
    2. Take the bus from Arequipa to Tacnabus bus
    3. Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus bus
    4. Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus bus
    35h 55m

Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) flights

Calendar19Weekly Planes
Duration8h 27mAverage Duration
Ticket$160Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Cusco, Peru and La Serena, Chile?

LATAM Chile flies from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) 3 times a day. Alternatively, you can take a bus from Cusco to Terminal de buses La Serena via Arequipa, Tacna, Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, and Terminal Rodoviario de Arica in around 35h 55m.

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