There are 5 ways to get from Cusco to La Serena by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC)plane CUZ - LSC
5h 16m$160–550Bus
cheapest- Take the bus from Cusco Bus Station to Tacna Bus Stationbus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
42h 50m$79–170Bus, drive
- Take the bus from Cusco to Arequipabus
- Take the bus from Arequipa to Tacnabus
- Drive from Tacna to El Roble / Dr. Amador Neghmecar
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
33h 43mDrive 2,408 km
- Drive from Cusco to La Serenacar 2,408 km
33h 57m$362–523Bus via Arequipa
- Take the bus from Cusco to Arequipabus
- Take the bus from Arequipa to Tacnabus
- Take the bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal de buses La Serenabus
35h 55m
Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) flights
Comparing Your Travel Options
The cheapest way to get from Cusco to La Serena is to bus which costs $75 - $170 and takes 42h 50m.
The fastest way to get from Cusco to La Serena is to fly which takes 5h 16m and costs $160 - $550.
No, there is no direct bus from Cusco to La Serena. However, there are services departing from Cusco and arriving at Terminal de buses La Serena via Arequipa, Terminal Terrestre Internacional Manuel A. Odría and Terminal Rodoviario de Arica. The journey, including transfers, takes approximately 35h 55m.
The distance between Cusco and La Serena is 1823 km. The road distance is 2408 km.
The best way to get from Cusco to La Serena without a car is to bus via Arequipa which takes 35h 55m and costs .
It takes approximately 5h 16m to fly from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC), including transfers and time at the airport.
Cusco to La Serena bus services, operated by Andoriña Tours, depart from Cusco station.
The best way to get from Cusco to La Serena is to fly which takes 5h 16m and costs $160 - $550. Alternatively, you can bus via Arequipa, which costs and takes 35h 55m.
There is no direct flight from Alejandro Velasco Astete International Airport Airport to La Florida Airport Airport. The quickest flight takes 5h 16m and has one stopover.
Cusco to La Serena bus services, operated by Andoriña Tours, arrive at Arequipa station.
What companies run services between Cusco, Peru and La Serena, Chile?
LATAM Chile flies from Alejandro Velasco Astete International Airport (CUZ) to La Florida Airport (LSC) 3 times a day. Alternatively, you can take a bus from Cusco to Terminal de buses La Serena via Arequipa, Tacna, Terminal Terrestre Internacional Manuel A. Odría, Terminal Internacional Arica, and Terminal Rodoviario de Arica in around 35h 55m.
- Website
- latam.com
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Santiago
- Ave. Duration
- 5h 16m
- When
- Wednesday and Sunday
- Estimated price
- $160–550
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Lima, Santiago
- Ave. Duration
- 9h 19m
- When
- Every day
- Estimated price
- $190–600
Flights from Alejandro Velasco Astete International Airport to La Florida Airport via Lima, Antofagasta
- Ave. Duration
- 9h 2m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $160–550
- Phone
- +51 993 585 217
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
- Phone
- +51 953 954 708
- [email protected]
- Website
- Transporte Moquegua Turismo
Bus from Arequipa to Tacna
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- Transporte Moquegua Turismo
Bus from Arequipa to Tacna
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- Transporte Moquegua Turismo
- [email protected]
- Website
- Pullman San Andres
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h
- Frequency
- Every 4 hours
- Estimated price
- $58–110
- Schedules at
- Pullman San Andres
- Semi Cama
- $70–95
- Cama
- $75–110
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h
- Frequency
- Every 4 hours
- Estimated price
- $58–110
- Schedules at
- Pullman San Andres
- Semi Cama
- $70–95
- Cama
- $75–110
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h 20m
- Frequency
- Twice daily
- Estimated price
- $50–68
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $50–60
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 23h 20m
- Frequency
- Twice daily
- Estimated price
- $50–68
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $50–60
- Phone
- +51904244509
- [email protected]
- Website
- aeroexpreso.com.pe
Bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Arica
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $3–26
- Schedules at
- aeroexpreso.com.pe
- Book at
- aeroexpreso.com.pe
Bus from Terminal Terrestre Internacional Manuel A. Odría to Terminal Internacional Arica
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $3–26
- Schedules at
- aeroexpreso.com.pe
- Book at
- aeroexpreso.com.pe
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 22h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–80
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $35–50
- Cama
- $55–80
- Premium
- $65–80
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 22h 30m
- Frequency
- Twice daily
- Estimated price
- $30–52
- Book at
- Recorrido Pluss Chile
- Semi Cama
- $30–40
- Cama
- $46–52
- Phone
- +56 57 226 9210
- [email protected]
- Website
- Ramos Cholele
Bus from Terminal Rodoviario de Arica to Terminal de buses La Serena
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $30–49
- Schedules at
- Ramos Cholele
- Semi cama
- $30–45
- Salón cama
- $45–49
Bus from Cusco Bus Station to Tacna Bus Station
- Ave. Duration
- 15h 30m
- Frequency
- Twice daily
- Estimated price
- $26–35
- Schedules at
- Expreso Turismo San Martin Nobleza
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Booking & Getting There
La Serena is 2h ahead of Cusco. It is currently 9:36 PM in Cusco and 11:36 PM in La Serena.
Yes, the driving distance between Cusco to La Serena is 2408 km. It takes approximately 33h 57m to drive from Cusco to La Serena.
LATAM Chile offers flights from Alejandro Velasco Astete International Airport Airport to La Florida Airport Airport.
There are 1049+ hotels available in La Serena.























