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How to get fromCusco to Medellínby plane, bus, or car

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There are 6 ways to get from Cusco to Medellín by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Medellin Jose Marie Cordova

    best
    1. Fly from Alejandro Velasco Astete International Airport (CUZ) to Medellin Jose Marie Cordova (MDE)plane plane CUZ - MDE
    6h 35m
    $188–528

  2. Bus

    cheapest
    1. Take the bus from Cusco to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Terminal Terrestre Quitumbebus bus
    3. Take the bus from Terminal Terrestre Quitumbe to Tulcánbus bus
    4. Take the bus from Terminal de Transporte Ipiales to Terminal del Surbus bus
    3d 12h
    $141–248

  3. Bus via Tumbes

    1. Take the bus from Cusco to Limabus bus
    2. Take the bus from Lima Paseo de la República to Tumbesbus bus
    3. Take the bus from Huaquillas to Yantzazabus bus
    4. Take the bus from Yantzaza to El Panguibus bus
    5. Take the bus from El Pangui to Lago Agríobus bus
    6. Take the bus from La Dorada, Putumayo to Terminal del Nortebus bus
    3d 3h
    $178–265

  4. Drive  3,903.2 km

    1. Drive from Cusco to Medellíncar car 3,903.2 km
    2d 14h
    $587–848

  5. Fly to Enrique Olaya Herrera Airport

    1. Fly from Alejandro Velasco Astete International Airport (CUZ) to Enrique Olaya Herrera Airport (EOH)plane plane CUZ - EOH
    8h 29m
    $600–2,000

  6. Bus #2

    1. Take the bus from Cusco to Gran Terminal Terrestre Plaza Nortebus bus
    2. Take the bus from Lima Plaza Norte to Terminal Terrestre Quitumbebus bus
    3. Take the bus from Terminal Terrestre Quitumbe to Lago Agríobus bus
    4. Take the bus from San Miguel to Terminal Salitrebus bus
    5. Take the bus from Terminal Salitre to Terminal del Nortebus bus
    4d 5h
    $160–293

Alejandro Velasco Astete International Airport (CUZ) to Medellin Jose Marie Cordova (MDE) flights

Calendar36Weekly Planes
Duration6h 59mAverage Duration
Ticket$135Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cusco to Medellín.ExpandLaunch map view
  • Distance: 2,248 km
  • Duration: 6h 35m

What companies run services between Cusco, Peru and Medellín, Colombia?

Avianca - Aerovías del Continente Americano S.A., JetSMART, and LATAM Chile fly from Alejandro Velasco Astete International Airport (CUZ) to Medellin Jose Marie Cordova (MDE) 5 times a day. Alternatively, you can take a bus from Cusco to Terminal del Norte via Lima, Lima Paseo de la República, Tumbes, Huaquillas, Yantzaza, El Pangui, Lago Agrío, and La Dorada, Putumayo in around 3d 3h.

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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including The beginner’s guide to the 2018 World Nomad Games, Italian Lakes: Getting around by train, and How to get from Gatwick Airport into central London - to help you get the most out of your next trip.