How to get fromCusco to Panamaby plane, bus, ferry, or car

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There are 2 ways to get from Cusco to Panama by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Alejandro Velasco Astete International Airport (CUZ) to Tocumen International Airport (PTY)plane CUZ - PTY
6h 52m
$325–518
Bus, ferry, drive
1. Take the bus from Cusco to Gran Terminal Terrestre Plaza Nortebus
2. Take the bus from Gran Terminal Terrestre Plaza Norte to Cúcutabus
3. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
4. Take the ferry from Cartagena to Portobeloferry
5. Drive from Portobelo to Panama Citycar
9d 19h
$1,018–1,115

Alejandro Velasco Astete International Airport (CUZ) to Tocumen International Airport (PTY) flights

33Weekly Planes

6h 26mAverage Duration

$120Cheapest Price

Questions & Answers

Map of how to get from Cusco to Panama.

Launch map view

Distance: 2,667.2 km
Duration: 6h 52m

What companies run services between Cusco, Peru and Panama?

Avianca - Aerovías del Continente Americano S.A., LATAM Chile, and two other airlines fly from Alejandro Velasco Astete International Airport (CUZ) to Tocumen International Airport (PTY) 5 times a day.

Airlines

Bus operators

Ferry operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from London City Airport into central London, Heading to Europe? Read this before you buy a Eurail Pass, and How do I buy a London Underground ticket? - to help you get the most out of your next trip.

Panama City, Panama(opens in a new window)

Panama City, also known as Panama (or Panamá in Spanish), is the capital and largest city of Panama. It has a total population of 1,938,000, with over 1,500,000 in its urban area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for banking and commerce.

Places to stay in Panama City

Plaza Paitilla Inn(Opens in a new window)

8.9Fabulous

Ramada Plaza by Wyndham Panama Punta Pacifica(Opens in a new window)

9.2Superb

Megapolis Hotel Panama(Opens in a new window)

8.5Very Good

Global Hotel Panama(Opens in a new window)

8.6Fabulous

Rome2Rio makes travelling from Cusco to Panama easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Cusco to Panama right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.