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How to get fromCusco to San Franciscoby bus or car

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There are 3 ways to get from Cusco to San Francisco by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive via Santa Ana

    best
    1. Take the bus from Terminal Terrestre Cusco to Terminal Terrestre Quillabambabus bus Cusco-Quillabamba
    2. Drive from Terminal Terrestre Quillabamba to San Franciscocar car
    10h 5m
    $52–77

  2. Drive 472.7 km

    1. Drive from Cusco to San Franciscocar car 472.7 km
    8h 56m
    $71–103

  3. Bus, drive

    1. Take the bus from Cusco to Andahuaylasbus bus Cusco
    2. Drive from Andahuaylas to San Franciscocar car
    16h 7m
    $74–118

Questions & Answers

Map of how to get from Cusco to San Francisco.ExpandLaunch map view
  • Distance: 491.5 km
  • Duration: 10h 5m

What companies run services between Cusco, Peru and San Francisco, Cusco, Peru?

There is no direct connection from Cusco to San Francisco. However, you can take the bus to Terminal Terrestre Quillabamba then drive to San Francisco. Alternatively, you can drive from Cusco to San Francisco in around 8h 56m.

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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Getting to Milan from the airport, How to get from Luton Airport into central London, and The beginner’s guide to the 2018 World Nomad Games - to help you get the most out of your next trip.