There are 3 ways to get from Cusco to São Luís by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Alejandro Velasco Astete International Airport (CUZ) to São Luís Airport (SLZ)plane CUZ - SLZ
9h 9mR$1,655–4,772Bus
- Take the bus from Cusco to Cuiabá, Terminal Rodoviáriobus
- Take the bus from Cuiabá, Terminal Rodoviário to Terminal Rodoviário de Santa Inês, MAbus
- Take the bus from Terminal Rodoviário de Santa Inês to Rodoviária de São Luísbus
4d 4hR$2,403–4,321Drive 4,927.9 km
- Drive from Cusco to São Luíscar 4,927.9 km
3d 7hR$4,085–5,900
Alejandro Velasco Astete International Airport (CUZ) to São Luís Airport (SLZ) flights
Comparing Your Travel Options
The cheapest way to get from Cusco to São Luís is to bus which costs R$ 2400 - R$ 4400 and takes 4 days 4h.
The fastest way to get from Cusco to São Luís is to fly which takes 9h 9m and costs R$ 1600 - R$ 4800.
No, there is no direct bus from Cusco to São Luís. However, there are services departing from Cusco and arriving at Rodoviária de São Luís via Cuiabá, Terminal Rodoviário and Terminal Rodoviário de Santa Inês. The journey, including transfers, takes approximately 4 days 4h.
The distance between Cusco and São Luís is 3291 km. The road distance is 4927.9 km.
The best way to get from Cusco to São Luís without a car is to bus which takes 4 days 4h and costs R$ 2400 - R$ 4400.
It takes approximately 9h 9m to get from Cusco to São Luís, including transfers.
Cusco to São Luís bus services, operated by Trans Acreana LTDA, depart from Cusco station.
The best way to get from Cusco to São Luís is to fly which takes 9h 9m and costs R$ 1600 - R$ 4800. Alternatively, you can bus, which costs R$ 2400 - R$ 4400 and takes 4 days 4h.
Cusco to São Luís bus services, operated by Trans Acreana LTDA, arrive at Cuiabá, Terminal Rodoviário station.
São Luís is 2h ahead of Cusco. It is currently 8:17 AM in Cusco and 10:17 AM in São Luís.
What companies run services between Cusco, Peru and São Luís, Brazil?
LATAM Chile flies from Alejandro Velasco Astete International Airport (CUZ) to São Luís Airport (SLZ) 4 times a day. Alternatively, you can take a bus from Cusco to São Luís via Cuiabá, Terminal Rodoviário, Terminal Rodoviário de Santa Inês, and Rodoviária de São Luís in around 4d 4h.
- Website
- latam.com
Flights from Alejandro Velasco Astete International Airport to São Luís Airport via Sao Paulo
- Ave. Duration
- 8h 55m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- R$1,600–4,800
Flights from Alejandro Velasco Astete International Airport to São Luís Airport via Lima, Brasilia
- Ave. Duration
- 10h 50m
- When
- Every day
- Estimated price
- R$1,600–4,800
Flights from Alejandro Velasco Astete International Airport to São Luís Airport via Lima, Sao Paulo
- Ave. Duration
- 14h 38m
- When
- Every day
- Estimated price
- R$1,800–5,500
- Phone
- +55 (68) 3221-1660
- Website
- transacreana.com.br
Bus from Cusco to Cuiabá, Terminal Rodoviário
- Ave. Duration
- 2d 5h
- Frequency
- Once a week
- Estimated price
- R$1,100–1,800
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
- Phone
- 0800 707 3838
- [email protected]
- Website
- satelitenorte.com.br
Bus from Cuiabá, Terminal Rodoviário to Terminal Rodoviário de Santa Inês, MA
- Ave. Duration
- 40h 9m
- Frequency
- Once daily
- Estimated price
- R$1,100–2,300
- Book at
- satelitenorte.queropassagem.com.br
Bus from Terminal Rodoviário de Santa Inês to Rodoviária de São Luís
- Ave. Duration
- 5h 4m
- Frequency
- Twice daily
- Estimated price
- R$95–210
- Book at
- satelitenorte.queropassagem.com.br
- Phone
- +55 98 3199 5000
- [email protected]
- Website
- Aguiar
Bus from Terminal Rodoviário de Santa Inês to Rodoviária de São Luís
- Ave. Duration
- 5h
- Frequency
- 4 times a day
- Estimated price
- R$100–160
- Schedules at
- Aguiar
- Phone
- 08005 518666
- [email protected]
- Website
- viacaoouroeprata.com.br
Bus from Terminal Rodoviário de Santa Inês to Rodoviária de São Luís
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- R$120–190
- Schedules at
- viacaoouroeprata.com.br
- Book at
- viacaoouroeprata.com.br
- Phone
- +55 800 728 1992
- [email protected]
- Website
- expressoguanabara.com.br
Bus from Terminal Rodoviário de Santa Inês to Rodoviária de São Luís
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- R$95–120
- Schedules at
- expressoguanabara.com.br
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Booking & Getting There
Yes, the driving distance between Cusco to São Luís is 4928 km. It takes approximately 3 days 7h to drive from Cusco to São Luís.
There are 557+ hotels available in São Luís.

















