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How to get fromDanville to St. Louisby train, plane, bus (Greyhound, Flixbus), bus, car, bus (Greyhound, Flixbus, Amtrak), or train (Amtrak)

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There are 10 ways to get from Danville to St. Louis by train, plane, bus (Greyhound, Flixbus), bus, car, bus (Greyhound, Flixbus, Amtrak), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Piedmont Triad International Airport, fly

    best
    1. Take the train from Danville Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    6h 56m
    $178–824

  2. Drive 716.2 mi

    cheapest
    1. Drive from Danville to St. Louiscar car 716.2 mi
    13h 8m
    $131–189

  3. Bus

    1. Take the bus from Danville Transit System Hub to Kemper Street Stationbus bus
    2. Take the bus from Lynchburg Transit Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    20h 15m
    $135–254

  4. Train, bus

    1. Take the train from Danville Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    23h 44m
    $264–551

  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Danville Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    7h 56m
    $163–751

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Danville Station to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Lambert–St. Louis International Airport (STL)plane plane LYH - STL
    9h 2m
    $135–647

  7. Train, train to Raleigh-Durham International Airport, fly

    1. Take the train from Danville Station to Greensborotrain train
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    3. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    8h 12m
    $589–1,080

  8. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Danville Station to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    8h 54m
    $237–535

  9. Bus via Carbondale

    1. Take the bus from Danville Transit System Hub to Kemper Street Stationbus bus
    2. Take the bus from Lynchburg Transit Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    20h 25m
    $135–264

  10. Train (Amtrak)

    1. Take the train from Danville Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    30h 5m
    $374–821

Danville to St. Louis by bus

Calendar7Weekly Buses
Duration20h 15mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Danville to St. Louis.ExpandLaunch map view
  • Distance: 674.1 mi
  • Duration: 6h 56m

What companies run services between Danville, VA, USA and St. Louis, MO, USA?

You can take a bus from Danville Transit System Hub to St Louis Bus Station via Kemper Street Station, Lynchburg Transit Center, and Nashville Bus Station in around 20h 15m. Alternatively, you can take a train from Danville Station to St. Louis via Charlottesville and Chicago Union Station in around 30h 5m.

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