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How to get fromDarlington to Winston-Salemby bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

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There are 7 ways to get from Darlington to Winston-Salem by bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Florence to Raleigh Bus Stationbus bus FlixBus N2472
    2. Take the bus from Raleigh Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670 / ...
    6h 4m
    $60–96

  2. Drive 149.7 mi

    cheapest
    1. Drive from Darlington to Winston-Salemcar car 149.7 mi
    2h 51m
    $28–40

  3. Train, bus

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    7h 35m
    $114–214

  4. Fly to Piedmont Triad International Airport

    1. Fly from Florence Regional Airport (FLO) to Piedmont Triad International Airport (GSO)plane plane FLO - GSO
    4h 49m
    $124–530

  5. Train, bus via Fayetteville

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0647S
    6h 47m
    $84–131

  6. Bus via Fayetteville

    1. Take the bus from Florence, SC to Fayetteville, NCbus bus Florence
    2. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0647S
    8h 26m
    $77–109

  7. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Florence Regional Airport (FLO) to Charlotte Douglas International Airport (CLT)plane plane FLO - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4h 48m
    $101–483

Florence Regional Airport (FLO) to Piedmont Triad International Airport (GSO) flights

Calendar28Weekly Planes
Duration5h 17mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Darlington to Winston-Salem.ExpandLaunch map view
  • Distance: 258.8 mi
  • Duration: 6h 4m

What companies run services between Darlington, SC, USA and Winston-Salem, NC, USA?

You can take a vehicle from Darlington to Winston Salem(Trans Center) via Florence and Raleigh Bus Station in around 6h 4m. Alternatively, American Airlines flies from Florence Regional Airport (FLO) to Piedmont Triad International Airport (GSO) 4 times a day.

Airlines
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Bus operators

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