There are 6 ways to get from Darmstadt to Palermo by plane, train (Trenitalia), bus, train, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Frankfurt
best- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 43m€85–212Train
- Take the train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
25h 19m€244–592Bus, train, ferry
- Take the bus from Mühlheim am Main to Lamezia Termebus
- Take the train from Lamezia Terme C to Villa S.Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
26h 29mDrive, car ferry
- Drive from Darmstadt to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
28h 15m€224–329Train to Stuttgart Airport, fly
- Take the train from Darmstadt Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane STR - PMO
6h 56m€102–333Bus
- Take the bus from Darmstadt Main Train Station Zweifalltorweg to Palermo Piazza Cairolibus
36h 10m€280–400
Frankfurt (FRA) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Darmstadt to Palermo is to fly which costs €80 - €220 and takes 5h 43m.
The fastest way to get from Darmstadt to Palermo is to fly which takes 5h 43m and costs €80 - €220.
Yes, there is a direct bus departing from Darmstadt Main Train Station Zweifalltorweg station and arriving at Palermo Piazza Cairoli. Services depart once a week, and operate Wednesday and Saturday. The journey takes approximately 36h 10m.
No, there is no direct train from Darmstadt to Palermo. However, there are services departing from Darmstadt Hauptbahnhof and arriving at Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 25h 19m.
The distance between Darmstadt and Palermo is 1425 km.
The best way to get from Darmstadt to Palermo without a car is to train which takes 25h 19m and costs €240 - €600.
It takes approximately 5h 43m to get from Darmstadt to Palermo, including transfers.
Darmstadt to Palermo bus services, operated by Onebus, depart from Darmstadt Main Train Station Zweifalltorweg.
Darmstadt to Palermo train services, operated by Deutsche Bahn Regio (DB Regional), depart from Darmstadt Hauptbahnhof station.
The best way to get from Darmstadt to Palermo is to fly which takes 5h 43m and costs €80 - €220. Alternatively, you can train, which costs €240 - €600 and takes 25h 19m, you could also bus, which costs €280 - €400 and takes 36h 10m.
What companies run services between Darmstadt, Germany and Palermo, Italy?
Lufthansa, ITA Airways, and Swiss fly from Frankfurt (FRA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a train from Darmstadt Hauptbahnhof to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 25h 19m.
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €95–200
Flights from Stuttgart Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–260
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Saturday, Sunday, and Friday
- Estimated price
- €70–280
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday to Sunday
- Estimated price
- €85–300
- Website
- eurowings.com
Flights from Stuttgart Airport to Palermo Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €65–260
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- €10–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Darmstadt Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- €26–55
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €70–120
- Website
- Italo Treno
Train from Lamezia Terme C to Villa S.Giovanni
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €13–22
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Mühlheim am Main to Lamezia Terme
- Ave. Duration
- 17h 49m
- Frequency
- Once a week
- Estimated price
- €170–230
- Website
- Onebus
Bus from Darmstadt Main Train Station Zweifalltorweg to Palermo Piazza Cairoli
- Ave. Duration
- 36h 10m
- Frequency
- Once a week
- Estimated price
- €280–400
- Website
- Onebus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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Booking & Getting There
Darmstadt to Palermo bus services, operated by Onebus, arrive at Palermo Piazza Cairoli station.
Darmstadt to Palermo train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Book your Darmstadt to Palermo train tickets online with Omio.
Book your Darmstadt to Palermo bus tickets online with Omio.
There are 6153+ hotels available in Palermo.










































