There are 9 ways to get from Darmstadt to Siena by plane, train, train (Trenitalia), bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 23m€135–297Train, bus
cheapest- Take the train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the bus from Mannheim central bus station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
19h 12m€95–183Train
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 43m€241–403Bus
- Take the bus from Darmstadt Main Train Station Zweifalltorweg to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 1518 / ...
16h 16m€140–192Train, night train
- Take the train from Darmstadt Hauptbahnhof to Hauptbahnhoftrain 62 / ...
- Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
18h 37m€113–262Fly to Pisa International Airport, train
- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 20m€125–285Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
6h 56m€119–290Fly to Venice Marco Polo Airport, train
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 37m€128–277Drive 992.9 km
- Drive from Darmstadt to Sienacar 992.9 km
9h 36m€161–233
Darmstadt to Siena by train
Comparing Your Travel Options
The cheapest way to get from Darmstadt to Siena is to train and bus which costs €95 - €190 and takes 19h 12m.
The fastest way to get from Darmstadt to Siena is to fly and train which takes 6h 20m and costs €120 - €290.
No, there is no direct bus from Darmstadt station to Siena. However, there are services departing from Darmstadt Main Train Station Zweifalltorweg and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 16m.
No, there is no direct train from Darmstadt to Siena. However, there are services departing from Darmstadt Hauptbahnhof and arriving at Siena via Frankfurt, Chiasso, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 43m.
The distance between Darmstadt and Siena is 848 km. The road distance is 992.9 km.
The best way to get from Darmstadt to Siena without a car is to train which takes 13h 43m and costs €240 - €410.
It takes approximately 6h 23m to get from Darmstadt to Siena, including transfers.
Darmstadt to Siena bus services, operated by Onebus, depart from Darmstadt Main Train Station Zweifalltorweg.
Darmstadt to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Frankfurt station.
The best way to get from Darmstadt to Siena is to train which takes 13h 43m and costs €240 - €410. Alternatively, you can bus, which costs €140 - €200 and takes 16h 16m.
What companies run services between Darmstadt, Germany and Siena, Italy?
You can take a train from Darmstadt Hauptbahnhof to Siena via Frankfurt, Chiasso, Milano Centrale, and Firenze S.M.N. in around 13h 43m. Alternatively, you can take a bus from Darmstadt Main Train Station Zweifalltorweg to Siena via Florence Villa Constanza Bus Station in around 16h 16m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €110–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 26m
- When
- Every day
- Estimated price
- €160–550
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €140–480
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–450
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €100–460
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €85–350
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €130–420
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €160–550
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €140–480
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €140–450
- Website
- condor.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–190
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €95–360
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 5m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €80–310
Flights from Frankfurt to Venice Marco Polo Airport via Zurich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €75–290
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €180–270
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €15–22
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €29–50
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €29–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Darmstadt Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- €28–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Twice daily
- Estimated price
- €45–130
- Website
- Nightjet
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–55
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Darmstadt Main Train Station Zweifalltorweg to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 26m
- Frequency
- Once a week
- Estimated price
- €130–190
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Mannheim central bus station to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- €80–130
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Want to know more about travelling around Italy
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Booking & Getting There
Darmstadt to Siena bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Darmstadt to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Chiasso station.
Yes, the driving distance between Darmstadt to Siena is 993 km. It takes approximately 9h 36m to drive from Darmstadt to Siena.
Book your Darmstadt to Siena train tickets online with Omio.
Book your Darmstadt to Siena bus tickets online with Omio.
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