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How to get fromDarmstadt to Sienaby plane, train, train (Trenitalia), bus, night train, or car

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There are 9 ways to get from Darmstadt to Siena by plane, train, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 53m
    €135–289

  2. Train, bus

    cheapest
    1. Take the train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the bus from Mannheim central bus station to Florence Villa Constanza Bus Stationbus bus N77
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    19h 12m
    €90–181

  3. Train

    1. Take the train from Frankfurt to Chiassotrain train Ec
    2. Take the train from Chiasso to Milano Centraletrain train S11
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    14h 25m
    €284–827

  4. Bus

    1. Take the bus from Darmstadt Main Train Station Zweifalltorweg to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    16h 20m
    €140–192

  5. Train, night train, bus

    1. Take the train from Darmstadt Hauptbahnhof to Hauptbahnhoftrain train 62 / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    19h 5m
    €107–302

  6. Fly to Pisa International Airport, train

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 41m
    €121–268

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 25m
    €121–284

  8. Fly to Venice Marco Polo Airport, train

    1. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 18m
    €118–280

  9. Drive  992.9 km

    1. Drive from Darmstadt to Sienacar car 992.9 km
    9h 36m
    €157–226

Darmstadt to Siena by train

Calendar6Weekly Trains
Duration14h 25mAverage Duration
Ticket€284Cheapest Price
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Questions & Answers

Map of how to get from Darmstadt to Siena.ExpandLaunch map view
  • Distance: 847.6 km
  • Duration: 6h 53m

What companies run services between Darmstadt, Germany and Siena, Italy?

You can take a train from Darmstadt Hauptbahnhof to Siena via Frankfurt, Chiasso, Milano Centrale, and Firenze S.M.N. in around 14h 25m. Alternatively, you can take a bus from Darmstadt Main Train Station Zweifalltorweg to Siena via Florence Villa Constanza Bus Station in around 16h 20m.

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