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How to get fromDarmstadt to Sienaby plane, train, train (Trenitalia), bus, night train, or car

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There are 10 ways to get from Darmstadt to Siena by plane, train, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 28m
    €135–286

  2. Bus via Frankfurt(Main)Hbf

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    19h 54m
    €89–147

  3. Train via Basel

    1. Take the train from Darmstadt Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 37m
    €127–684

  4. Bus

    1. Take the bus from Darmstadt Main Train Station Zweifalltorweg to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    16h 20m
    €140–191

  5. Train, night train

    1. Take the train from Darmstadt Hauptbahnhof to Hauptbahnhoftrain train 62 / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 17m
    €113–322

  6. Fly to Pisa International Airport, train

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 21m
    €119–263

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 52m
    €119–280

  8. Fly to Venice Marco Polo Airport, train

    1. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 34m
    €116–280

  9. Train

    1. Take the train from Frankfurt to Chiassotrain train Ec
    2. Take the train from Chiasso to Milano Centraletrain train S11
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 41m
    €274–835

  10. Drive 992.9 km

    1. Drive from Darmstadt to Sienacar car 992.9 km
    9h 36m
    €155–224

Darmstadt to Siena by train

Calendar76Weekly Trains
Duration13h 37mAverage Duration
Ticket€127Cheapest Price
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Questions & Answers

Map of how to get from Darmstadt to Siena.ExpandLaunch map view
  • Distance: 847.6 km
  • Duration: 6h 28m

What companies run services between Darmstadt, Germany and Siena, Italy?

You can take a train from Darmstadt Hauptbahnhof to Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 37m. Alternatively, you can take a bus from Darmstadt Main Train Station Zweifalltorweg to Siena via Florence Villa Constanza Bus Station in around 16h 20m.

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