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How to get fromDeBary to Knoxvilleby plane, bus, taxi, shuttle, car, or train

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There are 5 ways to get from DeBary to Knoxville by plane, bus, taxi, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando Sanford to Mcghee Tyson Airport

    best
    1. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3h 15m
    $264–1,072

  2. Drive  628.1 mi

    cheapest
    1. Drive from DeBary to Knoxvillecar car 628.1 mi
    10h 57m
    $111–161

  3. Bus, taxi, shuttle, drive

    1. Take the bus from Daytona Beach to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte to Boonebus bus
    3. Take the taxi from Boone to Black Bear Resorttaxi taxi
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Chilhowee at Holstoncar car
    20h 41m
    $413–513

  4. Train to Orlando, fly to Mcghee Tyson Airport

    1. Take the train from DeBary to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    5h 24m
    $212–979

  5. Fly Orlando Sanford to Asheville Regional Airport, drive

    1. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 4m
    $125–437

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar13Weekly Planes
Duration1h 37mAverage Duration
Ticket$161Cheapest Price
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Comparing Your Travel Options

Map of how to get from DeBary to Knoxville.ExpandLaunch map view
  • Distance: 539.5 mi
  • Duration: 3h 15m

What companies run services between DeBary, FL, USA and Knoxville, TN, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) twice daily.

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