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How to get fromDeKalb to Mayo Clinicby bus (Greyhound, Flixbus), train, bus, car, or plane

Find Transport to Mayo Clinic

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There are 6 ways to get from DeKalb to Mayo Clinic by bus (Greyhound, Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Dekalb to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    11h
    $111–164
  2. Drive 299.3 mi

    cheapest
    1. Drive from DeKalb to Mayo Cliniccar car 299.3 mi
    5h 10m
    $55–79
  3. Train, bus

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochester, MNbus bus
    13h 46m
    $168–329
  4. Train, fly to Rochester

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    7h 22m
    $68–332
  5. Train, bus via Madison

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 23m
    $84–149
  6. Train, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 57m
    $280–473

DeKalb to Mayo Clinic by bus, train, and foot

Calendar21Weekly Services
Duration13h 46mAverage Duration
Ticket$168Cheapest Price
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Questions & Answers

What companies run services between DeKalb, IL, USA and Mayo Clinic, MN, USA?

You can take a bus from Dekalb to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 11h.

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Train operators
Bus operators

Want to know more about travelling around United States

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