There are 6 ways to get from DeKalb to Mayo Clinic by bus (Greyhound, Flixbus), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Dekalb to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
11h$111–164Drive 299.3 mi
cheapest- Drive from DeKalb to Mayo Cliniccar 299.3 mi
5h 10m$55–79Train, bus
- Take the train from Elburn to Chicago OTCtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
13h 46m$168–329Train, fly to Rochester
- Take the train from Elburn to Chicago OTCtrain
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
7h 22m$68–332Train, bus via Madison
- Take the train from Elburn to Chicago OTCtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
12h 23m$84–149Train, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from Elburn to Chicago OTCtrain
- Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane ORD - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 57m$280–473
DeKalb to Mayo Clinic by bus, train, and foot
Questions & Answers
The cheapest way to get from DeKalb to Mayo Clinic is to drive which costs $50 - $80 and takes 5h 10m.
The fastest way to get from DeKalb to Mayo Clinic is to drive which takes 5h 10m and costs $50 - $80.
No, there is no direct bus from DeKalb to Mayo Clinic. However, there are services departing from Dekalb and arriving at Rochester via Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 11h.
The distance between DeKalb and Mayo Clinic is 439 miles. The road distance is 301 miles.
The best way to get from DeKalb to Mayo Clinic without a car is to bus which takes 11h and costs $110 - $170.
It takes approximately 11h to get from DeKalb to Mayo Clinic, including transfers.
DeKalb to Mayo Clinic bus services, operated by Greyhound USA, depart from Dekalb station.
DeKalb to Mayo Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between DeKalb to Mayo Clinic is 301 miles. It takes approximately 5h 10m to drive from DeKalb to Mayo Clinic.
There are 74+ hotels available in Mayo Clinic.
What companies run services between DeKalb, IL, USA and Mayo Clinic, MN, USA?
You can take a bus from Dekalb to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 11h.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $45–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $60–370
- Website
- united.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $60–370
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $60–370
- Website
- suncountry.com
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 46m
- When
- Monday, Friday, Thursday, and Sunday
- Estimated price
- $60–370
- Phone
- +1 312-696-3872
- Website
- metra.com
Train from Elburn to Chicago OTC
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- $6–8
- Website
- https://metra.com
- Adult
- $6–8
Train from Elburn to Chicago OTC
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- $6–8
- Website
- https://metra.com
- Adult
- $6–8
Train from Elburn to Chicago OTC
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- $6–8
- Website
- https://metra.com
- Adult
- $6–8
Train from Elburn to Chicago OTC
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- $6–8
- Website
- https://metra.com
- Adult
- $6–8
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Dekalb to Chicago Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $10–21
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Dekalb to Chicago Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- 3 times a day
- Estimated price
- $70–100
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–100
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–24
- Schedules at
- flixbus.com
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- coachusa.com
- Adult
- $25–55
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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