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How to get fromDeKalb to Mayo Clinicby bus (Greyhound, Flixbus), train, bus, car, or plane

Find Transport to Mayo Clinic

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There are 6 ways to get from DeKalb to Mayo Clinic by bus (Greyhound, Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Dekalb to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 58m
    $93–138

  2. Train, fly

    cheapest
    1. Take the train from Elburn to Chicago OTCtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    7h 20m
    $50–341

  3. Train, bus

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 41m
    $138–299

  4. Drive  299.3 mi

    1. Drive from DeKalb to Mayo Cliniccar car 299.3 mi
    5h 9m
    $55–79

  5. Train, bus via Milwaukee

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    11h 55m
    $100–169

  6. Train, bus via Madison

    1. Take the train from Elburn to Chicago OTCtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 24m
    $84–149

DeKalb to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration10h 58mAverage Duration
Ticket$93Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from DeKalb to Mayo Clinic.ExpandLaunch map view
  • Distance: 435 mi
  • Duration: 10h 58m

What companies run services between DeKalb, IL, USA and Mayo Clinic, MN, USA?

You can take a bus from Dekalb to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 10h 58m.

Airlines
Train operators
Bus operators

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