There are 9 ways to get from Decatur to Mayo Clinic by bus, plane, bus (Flixbus), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to University Of Illinois Willard Airport, fly to Rochester
best- Take the bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctrbus
- Fly from University Of Illinois Willard Airport (CMI) to Rochester (RST)plane CMI - RST
7h 5m$76–403Bus to Chicago O'Hare International Airport, fly to Rochester
cheapest- Take the bus from Decatur Downtown Transportation Center to Chicago Bus Stationbus
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
8h 10m$70–379Bus
- Take the bus from Decatur Downtown Transportation Center to Chicago Bus Stationbus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
13h 38m$102–174Bus, train
- Take the bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
15h 35m$190–406Drive 406.9 mi
- Drive from Decatur to Mayo Cliniccar 406.9 mi
8h 3m$75–108Bus to Abraham Lincoln Capital Airport, fly to Rochester
- Take the bus from Decatur Downtown Transportation Center to Springfield SMTD Transfer Centerbus
- Fly from Abraham Lincoln Capital Airport (SPI) to Rochester (RST)plane SPI - RST
6h 51m$76–407Fly Decatur Airport to Rochester
- Fly from Decatur Airport (DEC) to Rochester (RST)plane DEC - RST
6h 3m$71–397Bus to Lambert–St. Louis International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Decatur Downtown Transportation Center to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Minneapolis–Saint Paul International Airport (MSP)plane STL - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 36m$455–1,038Bus, train to Central Illinois Regional Airport At Bloomington-Normal, fly to Rochester
- Take the bus from Decatur Downtown Transportation Center to Springfield SMTD Transfer Centerbus
- Take the train from Springfield to Bloomington-Normaltrain
- Fly from Central Illinois Regional Airport At Bloomington-Normal (BMI) to Rochester (RST)plane BMI - RST
11h 14m$78–422
Decatur to Mayo Clinic by bus and foot
Questions & Answers
The cheapest way to get from Decatur to Mayo Clinic is to drive which costs $70 - $110 and takes 8h 3m.
The fastest way to get from Decatur to Mayo Clinic is to fly which takes 6h 3m and costs $70 - $400.
No, there is no direct bus from Decatur to Mayo Clinic. However, there are services departing from Decatur Downtown Transportation Center and arriving at Rochester via W Jackson Blvd, after S Clinton St and Madison. The journey, including transfers, takes approximately 13h 38m.
The distance between Decatur and Mayo Clinic is 410 miles. The road distance is 409.2 miles.
The best way to get from Decatur to Mayo Clinic without a car is to bus which takes 13h 38m and costs $100 - $180.
It takes approximately 7h 5m to get from Decatur to Mayo Clinic, including transfers.
Decatur to Mayo Clinic bus services, operated by Flixbus USA, depart from Decatur Downtown Transportation Center station.
The best way to get from Decatur to Mayo Clinic is to bus which takes 13h 38m and costs $100 - $180. Alternatively, you can fly, which costs $70 - $400 and takes 6h 3m.
Decatur to Mayo Clinic bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Yes, the driving distance between Decatur to Mayo Clinic is 409 miles. It takes approximately 8h 3m to drive from Decatur to Mayo Clinic.
What companies run services between Decatur, IL, USA and Mayo Clinic, MN, USA?
You can take a bus from Decatur Downtown Transportation Center to Mayo Clinic via Chicago Bus Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 13h 38m. Alternatively, United Airlines, American Airlines, and Delta fly from Decatur Airport (DEC) to Rochester (RST) twice daily.
- Website
- aa.com
Flights from University Of Illinois Willard Airport to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $50–330
Flights from Abraham Lincoln Capital Airport to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $55–340
Flights from Decatur Airport to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $55–340
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $40–290
Flights from Central Illinois Regional Airport At Bloomington-Normal to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $50–330
- Website
- delta.com
Flights from Decatur Airport to Rochester via Chicago O'Hare International Airport, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 52m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–370
Flights from Chicago O'Hare International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $50–320
Flights from Lambert–St. Louis International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $85–550
Flights from Central Illinois Regional Airport At Bloomington-Normal to Rochester via Atlanta, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 10h 11m
- When
- Every day
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $85–550
Flights from Lambert–St. Louis International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $100–600
- Website
- united.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–290
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Champaign-Urbana to Chicago Union Station
- Ave. Duration
- 2h 36m
- Frequency
- 3 times a day
- Estimated price
- $35–85
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $120–270
- Website
- Amtrak
Train from Springfield to Bloomington-Normal
- Ave. Duration
- 52 min
- Frequency
- 5 times a day
- Estimated price
- $18–40
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctr
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $7–12
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Chicago Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 5 times a week
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctr
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $7–12
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Springfield SMTD Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $5–10
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Chicago Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 5 times a week
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to St Louis Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a week
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Decatur Downtown Transportation Center to Springfield SMTD Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $5–10
- Schedules at
- Flixbus USA
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 68+ hotels available in Mayo Clinic.







