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How to get fromDeerfield to Knoxvilleby plane, bus (Flixbus), train, bus, or car

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There are 9 ways to get from Deerfield to Knoxville by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Mcghee Tyson Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    4h 9m
    $162–683

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 12m
    $89–388

  3. Bus via Farragut

    1. Take the bus from Chicago Bus Station to New York Midtownbus bus FlixBus N2641 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    32h 49m
    $328–499

  4. Train, bus

    1. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train Lake Shore Limited / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    35h 44m
    $498–909

  5. Drive 550.7 mi

    1. Drive from Deerfield to Knoxvillecar car 550.7 mi
    9h 44m
    $101–146

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Deerfield to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    4h 46m
    $192–881

  7. Fly Chicago O'Hare International Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 38m
    $135–691

  8. Train, bus via Ossining

    1. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    2. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    36h 21m
    $453–836

  9. Bus

    1. Take the bus from Chicago Bus Station to New York City Chinatownbus bus FlixBus N2640
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 54m
    $264–391

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration2h 58mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Deerfield to Knoxville.ExpandLaunch map view
  • Distance: 511.7 mi
  • Duration: 4h 9m

What companies run services between Deerfield, IL, USA and Knoxville, TN, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a train from Deerfield to Knoxville via Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 32h 49m.

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