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How to get fromDeerfield to St. Louisby train (Amtrak), bus (Flixbus), car, train, bus, or plane

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There are 6 ways to get from Deerfield to St. Louis by train (Amtrak), bus (Flixbus), car, train, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 45m
    $95–196

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    9h 45m
    $51–86

  3. Drive 309.2 mi

    1. Drive from Deerfield to St. Louiscar car 309.2 mi
    5h 15m
    $57–82

  4. Train, bus to Chicago O'Hare International Airport, fly

    1. Take the train from Deerfield to Edgebrooktrain train
    2. Take the bus from Lehigh & Devon to Jefferson Park Transit Centerbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 3m
    $280–716

  5. Train to Chicago Midway International Airport, fly

    1. Take the train from Deerfield to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 52m
    $90–564

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Glenview Amtrak Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 54m
    $510–916

Deerfield to St. Louis by train (Amtrak)

Calendar38Weekly Trains
Duration6h 45mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Deerfield to St. Louis.ExpandLaunch map view
  • Distance: 305 mi
  • Duration: 6h 45m

What companies run services between Deerfield, IL, USA and St. Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $45–80 and the journey takes 5h 55m.

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