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How to get fromDefiance to Lafayetteby bus (Amtrak), train (Amtrak), car, plane, taxi, or bus

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There are 5 ways to get from Defiance to Lafayette by bus (Amtrak), train (Amtrak), car, plane, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Amtrak)

    best
    1. Take the bus from Bryan Amtrak Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    7h 49m
    $144–206

  2. Drive 160.7 mi

    cheapest
    1. Drive from Defiance to Lafayettecar car 160.7 mi
    3h 4m
    $30–43

  3. Train (Amtrak)

    1. Take the train from Bryan Amtrak Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    8h 20m
    $146–266

  4. Drive, fly

    1. Drive from Defiance to Fort Wayne International Airport (FWA)car car
    2. Fly from Fort Wayne International Airport (FWA) to Purdue University Airport (LAF)plane plane FWA - LAF
    5h 20m
    $56–315

  5. Taxi, bus

    1. Take the taxi from Defiance to Green Streettaxi taxi
    2. Take the bus from Fort Wayne, IN to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Airport to Courtyard Lafayettebus bus
    8h 1m
    $153–220

Fort Wayne International Airport (FWA) to Purdue University Airport (LAF) flights

Calendar21Weekly Planes
Duration5h 54mAverage Duration
Ticket$46Cheapest Price
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Questions & Answers

Map of how to get from Defiance to Lafayette.ExpandLaunch map view
  • Distance: 330.6 mi
  • Duration: 7h 49m

What companies run services between Defiance, OH, USA and Lafayette, IN, USA?

You can take a vehicle from Defiance to Lafayette Amtrak Station via Bryan Amtrak Station and Chicago Union Station in around 7h 49m. Alternatively, you can take a vehicle from Defiance to Lafayette Amtrak Station via Bryan Amtrak Station and Chicago Union Station in around 8h 20m.

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