There are 5 ways to get from Deltona to Knoxville by plane, bus, taxi, shuttle, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando Sanford to Mcghee Tyson Airport
best- Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
3h 9m$221–906Fly Orlando Sanford to Asheville Regional Airport, drive
cheapest- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
4h 56m$113–421Bus, taxi, shuttle, drive
- Take the bus from Daytona Beach to Charlotte Bus Stationbus
- Take the bus from Charlotte to Boonebus
- Take the taxi from Boone to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Chilhowee at Holstoncar
20h 28m$409–503Drive 629 mi
- Drive from Deltona to Knoxvillecar 629 mi
10h 57m$115–166Train to Orlando, fly to Mcghee Tyson Airport
- Take the train from DeBary to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane MCO - TYS
5h 32m$192–879
Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Deltona to Knoxville is to drive which costs $110 - $170 and takes 10h 57m.
The fastest way to get from Deltona to Knoxville is to fly which takes 3h 9m and costs $220 - $950.
The distance between Deltona and Knoxville is 541 miles. The road distance is 632.7 miles.
It takes approximately 3h 9m to get from Deltona to Knoxville, including transfers.
Yes, the driving distance between Deltona to Knoxville is 633 miles. It takes approximately 10h 57m to drive from Deltona to Knoxville.
There are 326+ hotels available in Knoxville.
What companies run services between Deltona, FL, USA and Knoxville, TN, USA?
Allegiant Air flies from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) twice daily.
- Website
- allegiantair.com
Flights from Orlando Sanford to Mcghee Tyson Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $130–800
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 43m
- When
- Friday, Monday, and Wednesday
- Estimated price
- $130–800
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $55–350
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from DeBary to Sand Lake Road
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Daytona Beach to Charlotte Bus Station
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 13m
- Estimated price
- $120–150
High Country Taxi
- Phone
- +1 828-414-1492
- Website
- highcountrytaxi.com
Tipsy Taxi
- Phone
- +1 828-719-8477
- Website
- facebook.com
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