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How to get fromDenver Airport (DEN) to San Diegoby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Denver Airport (DEN) to San Diego by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Denver (DEN) to San Diego International Airport (SAN)plane plane DEN - SAN
    2h 20m
    $120–210

  2. Bus via Santa Ana

    1. Take the bus from Denver International Airport to Vail Transportation Centerbus bus
    2. Take the bus from Vail to Las Vegas Bus Terminalbus bus
    3. Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus bus
    4. Take the bus from Santa Ana Bus Stop to San Diegobus bus
    24h 47m
    $265–424

  3. Bus, train

    1. Take the bus from Denver to Las Vegas Transportation Centerbus bus
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    31h 35m
    $413–828

  4. Drive 1,101.9 mi

    1. Drive from Denver Airport (DEN) to San Diegocar car 1,101.9 mi
    17h 18m
    $202–291

  5. Bus

    1. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus Greyhound US1200
    2. Take the bus from Las Vegas Strip to San Diegobus bus FlixBus 2037
    27h 57m
    $202–367

Denver Airport (DEN) to San Diego by bus

Calendar7Weekly Buses
Duration24h 47mAverage Duration
Ticket$265Cheapest Price
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Questions & Answers

Map of how to get from Denver Airport (DEN) to San Diego.ExpandLaunch map view
  • Distance: 852 mi
  • Duration: 2h 20m

What companies run services between Denver Airport (DEN), USA and San Diego, CA, USA?

Frontier Airlines, United Airlines, and two other airlines fly from Denver (DEN) to San Diego International Airport (SAN) hourly. Alternatively, you can take a bus from Denver International Airport to San Diego via Vail, Las Vegas Bus Terminal, and Santa Ana Bus Stop in around 24h 47m.

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