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How to get fromDenver, CO to St. Louisby plane, bus (Greyhound), train (Amtrak), car, or bus

Find Transport to St. Louis

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There are 5 ways to get from Denver, CO to St. Louis by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Denver

    best
    1. Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane plane DEN - STL
    4h 36m
    $151–492

  2. Bus to Colorado Springs Airport, fly

    cheapest
    1. Take the bus from Denver, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to Lambert–St. Louis International Airport (STL)plane plane COS - STL
    8h 24m
    $130–623

  3. Bus (Greyhound)

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus Greyhound US1200 / ...
    17h 3m
    $150–230

  4. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train California Zephyr
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    24h 44m
    $718–1,112

  5. Drive  848.2 mi

    1. Drive from Denver, CO to St. Louiscar car 848.2 mi
    13h 22m
    $155–224

Denver, CO to St. Louis by foot and bus (Greyhound)

Calendar14Weekly Services
Duration17h 3mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Denver, CO to St. Louis.ExpandLaunch map view
  • Distance: 806.3 mi
  • Duration: 4h 36m

What companies run services between Denver, CO, USA and St. Louis, MO, USA?

Frontier Airlines, United Airlines, and Southwest Airlines fly from Denver (DEN) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Denver Union Station to St Louis Bus Station twice daily. Tickets cost $150–230 and the journey takes 16h 45m.

Airlines
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Need to know: Greyhound

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