There are 4 ways to get from Denver, CO to St. Louis by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane DEN - STL
4h 41m$193–223Bus (Greyhound)
cheapest- Take the bus from Denver Union Station to St Louis Bus Stationbus Greyhound US1200 / ...
16h 48m$140–270Train (Amtrak)
- Take the train from Denver to Chicago Union Stationtrain California Zephyr
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
24h 44m$427–865Drive 848.2 mi
- Drive from Denver, CO to St. Louiscar 848.2 mi
13h 22m$155–224
Denver, CO to St. Louis by foot and bus (Greyhound)
Questions & Answers
The cheapest way to get from Denver, CO to St. Louis is to bus which costs $140 - $270 and takes 16h 48m.
The fastest way to get from Denver, CO to St. Louis is to fly which takes 4h 41m and costs $190 - $230.
Yes, there is a direct bus departing from Denver Union Station station and arriving at St Louis Bus Station station. Services depart twice daily, and operate every day. The journey takes approximately 16h 30m.
No, there is no direct train from Denver, CO to St. Louis. However, there are services departing from Denver and arriving at St. Louis via Chicago Union Station. The journey, including transfers, takes approximately 24h 44m.
The distance between Denver, CO and St. Louis is 811 miles. The road distance is 853.1 miles.
The best way to get from Denver, CO to St. Louis without a car is to bus which takes 16h 48m and costs $140 - $270.
It takes approximately 4h 41m to get from Denver, CO to St. Louis, including transfers.
Denver, CO to St. Louis bus services, operated by Greyhound USA, depart from Denver Union Station.
Denver, CO to St. Louis train services, operated by Amtrak, depart from Denver station.
The best way to get from Denver, CO to St. Louis is to fly which takes 4h 41m and costs $190 - $230. Alternatively, you can bus, which costs $140 - $270 and takes 16h 48m, you could also train, which costs $420 - $900 and takes 24h 44m.
What companies run services between Denver, CO, USA and St. Louis, MO, USA?
Frontier Airlines, United Airlines, and Southwest Airlines fly from Denver (DEN) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, Greyhound USA operates a bus from Denver Union Station to St Louis Bus Station twice daily. Tickets cost $140–270 and the journey takes 16h 30m.
- Website
- southwest.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $110–600
- Website
- united.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $110–600
- Website
- flyfrontier.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $180–210
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $330–700
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Twice daily
- Estimated price
- $140–270
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Denver, CO to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
St. Louis is 1h ahead of Denver, CO. It is currently 10:18 PM in Denver, CO and 11:18 PM in St. Louis.
Denver, CO to St. Louis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Denver, CO to St. Louis is 853 miles. It takes approximately 13h 22m to drive from Denver, CO to St. Louis.
Book your Denver, CO to St. Louis train tickets online with Omio.
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