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How to get fromDenver to Chicagoby plane, bus, train, bus (Flixbus), car, or taxi

Find Transport to Chicago

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There are 8 ways to get from Denver to Chicago by plane, bus, train, bus (Flixbus), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lancaster to Chicago O'Hare International Airport

    best
    1. Fly from Lancaster (LNS) to Chicago O'Hare International Airport (ORD)plane plane LNS - ORD
    3h 35m
    $88–338

  2. Bus, train

    1. Take the bus from Reading to Pittsburgh Intermodal Stationbus bus FlixBus 2642 / ...
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    17h 5m
    $332–518

  3. Bus (Flixbus)

    1. Take the bus from Reading to Chicago Bus Stationbus bus FlixBus N2642
    19h 4m
    $162–238

  4. Drive  698.3 mi

    1. Drive from Denver to Chicagocar car 698.3 mi
    11h 33m
    $128–185

  5. Taxi to Harrisburg International Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Denver to Harrisburg-Airport-MDTtaxi taxi
    2. Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane plane MDT - ORD
    4h 4m
    $178–444

  6. Bus to Philadelphia International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    6h 16m
    $196–434

  7. Bus to Lehigh Valley International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Reading to Allentownbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    6h 46m
    $90–353

  8. Taxi, train

    1. Take the taxi from Denver to Elizabethtown Amtrak Stationtaxi taxi
    2. Take the train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    17h 33m
    $493–750

Lancaster (LNS) to Chicago O'Hare International Airport (ORD) flights

Calendar12Weekly Planes
Duration2h 23mAverage Duration
Ticket$52Cheapest Price
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Comparing Your Travel Options

Map of how to get from Denver to Chicago.ExpandLaunch map view
  • Distance: 649.5 mi
  • Duration: 3h 35m

What companies run services between Denver, PA, USA and Chicago, IL, USA?

United Airlines flies from Lancaster (LNS) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, Flixbus USA operates a bus from Reading to Chicago Bus Station 3 times a week. Tickets cost $130–200 and the journey takes 18h 40m.

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