There are 6 ways to get from Denver to Cape Girardeau by plane, bus, bus (Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lambert–St. Louis International Airport, bus
best- Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane DEN - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 27m$208–351Fly to Cape Girardeau Municipal Airport
cheapest- Fly from Denver (DEN) to Cape Girardeau Municipal Airport (CGI)plane DEN - CGI
7h 42m$145–417Bus (Greyhound)
- Take the bus from Denver Union Station to St Louis Bus Stationbus Greyhound US1200 / ...
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
19h 54m$166–255Drive 943 mi
- Drive from Denver to Cape Girardeaucar 943 mi
15h 5m$173–249Fly to Memphis, bus
- Fly from Denver (DEN) to Memphis (MEM)plane DEN - MEM
- Take the bus from Memphis Bus Station to Cape Girardeaubus
9h 28m$243–424Fly to Nashville, bus, taxi
- Fly from Denver (DEN) to Nashville (BNA)plane DEN - BNA
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
- Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi
10h 39m$312–684
Denver (DEN) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Denver to Cape Girardeau is to bus which costs $160 - $260 and takes 19h 54m.
The fastest way to get from Denver to Cape Girardeau is to fly and bus which takes 7h 27m and costs $200 - $360.
No, there is no direct bus from Denver station to Cape Girardeau. However, there are services departing from Denver Union Station and arriving at Cape Girardeau via St Louis Bus Station. The journey, including transfers, takes approximately 19h 54m.
The distance between Denver and Cape Girardeau is 926 miles. The road distance is 948.5 miles.
The best way to get from Denver to Cape Girardeau without a car is to bus which takes 19h 54m and costs $160 - $260.
It takes approximately 7h 27m to get from Denver to Cape Girardeau, including transfers.
Denver to Cape Girardeau bus services, operated by Greyhound USA, depart from Denver Union Station.
The best way to get from Denver to Cape Girardeau is to bus which takes 19h 54m and costs $160 - $260. Alternatively, you can fly, which costs $140 - $420 and takes 7h 42m.
Denver to Cape Girardeau bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Cape Girardeau is 1h ahead of Denver. It is currently 5:53 AM in Denver and 6:53 AM in Cape Girardeau.
What companies run services between Denver, CO, USA and Cape Girardeau, MO, USA?
You can take a bus from Denver Union Station to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 19h 54m. Alternatively, United Airlines, Corporate Flight Management Inc, and two other airlines fly from Denver (DEN) to Cape Girardeau Municipal Airport (CGI) 3 times a day.
- Website
- southwest.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $95–550
Flights from Denver to Lambert–St. Louis International Airport via Kansas City
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $95–550
Flights from Denver to Memphis
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $150–800
Flights from Denver to Memphis via Dallas
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $170–850
Flights from Denver to Memphis via Houston Hobby Apt
- Ave. Duration
- 4h 48m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
Flights from Denver to Memphis via Austin
- Ave. Duration
- 5h
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–950
Flights from Denver to Nashville
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $95–500
Flights from Denver to Nashville via Kansas City
- Ave. Duration
- 4h 13m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Denver to Nashville via Lambert–St. Louis International Airport
- Ave. Duration
- 4h 5m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–500
- Website
- united.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $95–550
Flights from Denver to Memphis
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $150–800
Flights from Denver to Nashville
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $95–500
- Website
- flyfrontier.com
Flights from Denver to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 3m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $180–310
Flights from Denver to Memphis
- Ave. Duration
- 2h 19m
- When
- Thursday and Sunday
- Estimated price
- $200–370
Flights from Denver to Nashville
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $180–260
- Website
- contouraviation.com
Flights from Denver to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $95–470
Flights from Denver to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 11m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–460
- Website
- aa.com
Flights from Denver to Memphis via Dallas/Ft.Worth
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $140–220
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Memphis Bus Station to Cape Girardeau
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Denver to Cape Girardeau is 948 miles. It takes approximately 15h 5m to drive from Denver to Cape Girardeau.
Book your Denver to Cape Girardeau bus tickets online with Omio.
There are 25+ hotels available in Cape Girardeau.



