There are 7 ways to get from Denver to Clarksdale by plane, car, bus, taxi, train (Amtrak), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Bill And Hillary Clinton National Airport, drive
best- Fly from Denver (DEN) to Bill And Hillary Clinton National Airport (LIT)plane DEN - LIT
- Drive from Bill And Hillary Clinton National Airport (LIT) to Clarksdalecar
6h 30m$100–435Bus, taxi
- Take the bus from Denver Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus
- Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi
26h 20m$330–475Train (Amtrak)
- Take the train from Denver to Chicago Union Stationtrain California Zephyr
- Take the train from Chicago Union Station to Marks Stationtrain City of New Orleans
32h 24m$938–1,437Drive 1,081.6 mi
- Drive from Denver to Clarksdalecar 1,081.6 mi
17h 50m$198–286Fly to Memphis, bus, taxi
- Fly from Denver (DEN) to Memphis (MEM)plane DEN - MEM
- Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus
- Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi
8h 14m$336–536Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Denver (DEN) to Birmingham–Shuttlesworth International Airport (BHM)plane DEN - BHM
- Drive from Birmingham-Airport-BHM to Clarksdalecar
8h 39m$249–1,051Bus, train
- Take the bus from Denver Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Marks Stationtrain
27h 30m$371–567
Denver (DEN) to Bill And Hillary Clinton National Airport (LIT) flights
Comparing Your Travel Options
The cheapest way to get from Denver to Clarksdale is to drive which costs $190 - $290 and takes 17h 50m.
The fastest way to get from Denver to Clarksdale is to fly and drive which takes 6h 30m and costs $100 - $440.
No, there is no direct train from Denver to Clarksdale station. However, there are services departing from Denver and arriving at Marks Station via Chicago Union Station. The journey, including transfers, takes approximately 32h 24m.
The distance between Denver and Clarksdale is 940 miles. The road distance is 1087.9 miles.
The best way to get from Denver to Clarksdale without a car is to bus and taxi which takes 26h 20m and costs $330 - $480.
It takes approximately 6h 30m to get from Denver to Clarksdale, including transfers.
Denver to Clarksdale train services, operated by Amtrak, depart from Denver station.
Clarksdale is 1h ahead of Denver. It is currently 4:58 AM in Denver and 5:58 AM in Clarksdale.
Denver to Clarksdale train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Denver to Clarksdale is 1088 miles. It takes approximately 17h 50m to drive from Denver to Clarksdale.
What companies run services between Denver, CO, USA and Clarksdale, MS, USA?
You can take a train from Denver to Clarksdale via Chicago Union Station and Marks Station in around 32h 24m.
- Website
- southwest.com
Flights from Denver to Bill And Hillary Clinton National Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $75–400
Flights from Denver to Bill And Hillary Clinton National Airport via Dallas
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $85–430
Flights from Denver to Memphis
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $160–850
Flights from Denver to Memphis via Dallas
- Ave. Duration
- 4h 35m
- When
- Monday to Wednesday
- Estimated price
- $180–950
Flights from Denver to Memphis via Austin
- Ave. Duration
- 4h 47m
- When
- Tuesday to Friday
- Estimated price
- $220–1,100
Flights from Denver to Memphis via Houston Hobby Apt
- Ave. Duration
- 4h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,100
Flights from Denver to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Denver to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 4h 16m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $210–1,100
Flights from Denver to Birmingham–Shuttlesworth International Airport via Dallas
- Ave. Duration
- 4h 23m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,100
- Website
- united.com
Flights from Denver to Bill And Hillary Clinton National Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $75–400
Flights from Denver to Memphis
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $160–850
Flights from Denver to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $200–1,000
- Website
- aa.com
Flights from Denver to Bill And Hillary Clinton National Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $85–430
Flights from Denver to Memphis via Dallas/Ft.Worth
- Ave. Duration
- 4h 39m
- When
- Wednesday to Saturday
- Estimated price
- $180–950
- Website
- flyfrontier.com
Flights from Denver to Memphis
- Ave. Duration
- 2h 15m
- When
- Thursday and Sunday
- Estimated price
- $200–370
- Website
- delta.com
Flights from Denver to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $230–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Marks Station
- Ave. Duration
- 12h 20m
- Frequency
- Once daily
- Estimated price
- $320–500
- Website
- Amtrak
Train from Carbondale to Marks Station
- Ave. Duration
- 6h 31m
- Frequency
- Once daily
- Estimated price
- $150–250
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $150–230
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Memphis Bus Station to Batesville(Terza One Stop Shop)
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Memphis Bus Station to Batesville(Terza One Stop Shop)
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $150–230
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Batesville(Terza One Stop Shop)
- Ave. Duration
- 1h
- Frequency
- 5 times a week
- Estimated price
- $9–14
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Batesville(Terza One Stop Shop)
- Ave. Duration
- 1h
- Frequency
- 5 times a week
- Estimated price
- $9–14
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
- Ave. Duration
- 55 min
- Estimated price
- $120–150
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Booking & Getting There
There are 15+ hotels available in Clarksdale.









