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How to get fromDenver to Florence Stationby plane, bus (Greyhound, Amtrak, Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Denver to Florence Station by plane, bus (Greyhound, Amtrak, Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Denver (DEN) to Florence Regional Airport (FLO)plane plane DEN - FLO
    7h 41m
    $150–472

  2. Bus via Carbondale

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    36h 19m
    $261–518

  3. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    2d
    $722–1,539

  4. Drive 1,652.9 mi

    1. Drive from Denver to Florence Stationcar car 1,652.9 mi
    27h 38m
    $302–436

  5. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    36h 54m
    $261–508

Denver to Florence Station by train (Amtrak)

Calendar7Weekly Trains
Duration2dAverage Duration
Ticket$722Cheapest Price
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Questions & Answers

Map of how to get from Denver to Florence Station.ExpandLaunch map view
  • Distance: 1,450.8 mi
  • Duration: 7h 41m

What companies run services between Denver, CO, USA and Florence Station, SC, USA?

American Airlines and Frontier Airlines fly from Denver (DEN) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a bus from Denver Union Station to Florence Station via St Louis Bus Station, St. Louis, Carbondale Intermodal Station, Atlanta Bus Station, and Florence Bus Station in around 36h 19m.

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