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How to get fromDenver to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 9 ways to get from Denver to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Denver (DEN) to Mcghee Tyson Airport (TYS)plane plane DEN - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 17m
    $240–826

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Denver (DEN) to Asheville Regional Airport (AVL)plane plane DEN - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 41m
    $134–532

  3. Bus, drive

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    42h 3m
    $297–579

  4. Train, bus, drive

    1. Take the train from Denver to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    2d 4h
    $747–1,551

  5. Drive 1,370.2 mi

    1. Drive from Denver to Great Smoky Mountainscar car 1,370.2 mi
    23h 36m
    $251–362

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Denver (DEN) to Greenville–Spartanburg International Airport (GSP)plane plane DEN - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 57m
    $204–795

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Denver (DEN) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane DEN - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 39m
    $225–495

  8. Fly to Nashville, drive

    1. Fly from Denver (DEN) to Nashville (BNA)plane plane DEN - BNA
    2. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    8h 48m
    $230–675

  9. Bus, drive via Columbus

    1. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    46h 32m
    $282–570

Denver (DEN) to Mcghee Tyson Airport (TYS) flights

Calendar55Weekly Planes
Duration4h 6mAverage Duration
Ticket$188Cheapest Price
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Questions & Answers

Map of how to get from Denver to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 1,242.5 mi
  • Duration: 6h 17m

What companies run services between Denver, CO, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Denver to Great Smoky Mountains. However, you can take the train to Denver Airport Station, walk to Denver (DEN) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Denver Union Station to Great Smoky Mountains via St Louis Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 42h 3m.

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