There are 7 ways to get from Denver to Greenville by plane, bus (Greyhound, Flixbus), car, taxi, bus, train, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Denver to Greenville–Spartanburg International Airport
best- Fly from Denver (DEN) to Greenville–Spartanburg International Airport (GSP)plane DEN - GSP
5h 6m$215–805Bus
- Take the bus from Denver Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
34h 43m$283–594Drive 1,480.4 mi
- Drive from Denver to Greenvillecar 1,480.4 mi
24h 52m$271–391Fly Denver to Asheville Regional Airport, taxi
- Fly from Denver (DEN) to Asheville Regional Airport (AVL)plane DEN - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
5h 36m$260–680Bus to Colorado Springs Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Denver, CO to Colorado Springs, CObus
- Fly from Colorado Springs Airport (COS) to Greenville–Spartanburg International Airport (GSP)plane COS - GSP
8h 55m$222–865Train, bus
- Take the train from Denver to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
41h 9m$508–1,063Bus via Fort Worth
- Take the bus from Denver Union Station to Fort Worth Downtownbus
- Take the bus from Fort Worth Downtown to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
42h 45m$330–655
Denver (DEN) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Denver to Greenville is to drive which costs $270 - $390 and takes 24h 52m.
The fastest way to get from Denver to Greenville is to fly which takes 5h 6m and costs $210 - $850.
No, there is no direct bus from Denver station to Greenville. However, there are services departing from Denver Union Station and arriving at Taqueria Guadalajara - Greenville via St Louis Bus Station, Lindbergh Center Station - Bay D and Atlanta. The journey, including transfers, takes approximately 34h 43m.
The distance between Denver and Greenville is 1319 miles. The road distance is 1489 miles.
The best way to get from Denver to Greenville without a car is to bus which takes 34h 43m and costs $280 - $600.
It takes approximately 5h 6m to get from Denver to Greenville, including transfers.
Denver to Greenville bus services, operated by Greyhound USA, depart from Denver Union Station.
The best way to get from Denver to Greenville is to fly which takes 5h 6m and costs $210 - $850. Alternatively, you can bus, which costs $280 - $600 and takes 34h 43m.
Denver to Greenville bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Greenville is 2h ahead of Denver. It is currently 6:49 AM in Denver and 8:49 AM in Greenville.
What companies run services between Denver, CO, USA and Greenville, SC, USA?
United Airlines, Southwest Airlines, and two other airlines fly from Denver (DEN) to Greenville–Spartanburg International Airport (GSP) every 2 hours. Alternatively, you can take a bus from Denver Union Station to Greenville via St Louis Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 34h 43m.
- Website
- delta.com
Flights from Denver to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $170–800
Flights from Denver to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $120–550
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $170–800
- Website
- aa.com
Flights from Denver to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $180–800
Flights from Denver to Greenville–Spartanburg International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $190–850
Flights from Denver to Asheville Regional Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $120–550
Flights from Denver to Asheville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $120–550
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $180–800
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 9h 23m
- When
- Every day
- Estimated price
- $190–850
- Website
- united.com
Flights from Denver to Greenville–Spartanburg International Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- $170–750
Flights from Denver to Asheville Regional Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $110–500
Flights from Denver to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $120–550
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Denver
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $170–800
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $190–850
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Houston
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $200–900
- Website
- southwest.com
Flights from Denver to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 58m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $170–750
Flights from Colorado Springs Airport to Greenville–Spartanburg International Airport via Dallas, Nashville
- Ave. Duration
- 7h 32m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $190–850
- Website
- allegiantair.com
Flights from Denver to Asheville Regional Airport
- Ave. Duration
- 3h 2m
- When
- Monday and Friday
- Estimated price
- $110–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $330–700
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Twice daily
- Estimated price
- $130–250
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $110–210
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- 3 times a day
- Estimated price
- $120–240
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $90–160
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- Twice daily
- Estimated price
- $110–200
- Schedules at
- flixbus.com
Bus from Denver Union Station to Fort Worth Downtown
- Ave. Duration
- 16h 30m
- Frequency
- 6 times a week
- Estimated price
- $140–240
- Schedules at
- flixbus.com
Bus from Fort Worth Downtown to Dallas Bus Station
- Ave. Duration
- 55 min
- Frequency
- 6 times a week
- Estimated price
- $5–9
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
- Phone
- +1 719-348-5562
- [email protected]
- Website
- eccog.com
Bus from Denver, CO to Colorado Springs, CO
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $12–16
- Schedules at
- eccog.com
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More Questions & Answers
Yes, the driving distance between Denver to Greenville is 1489 miles. It takes approximately 24h 52m to drive from Denver to Greenville.
Book your Denver to Greenville bus tickets online with Omio.
There are 273+ hotels available in Greenville.











