Rome2Rio

How to get fromDenver to Lake Cityby plane, bus, bus (Flixbus), train, car, or bus (Greyhound, Flixbus)

Find Transport to Lake City

See all options

There are 8 ways to get from Denver to Lake City by plane, bus, bus (Flixbus), train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville, bus

    best
    1. Fly from Denver (DEN) to Jacksonville (JAX)plane plane DEN - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    8h 33m
    $149–630

  2. Fly to Gainesville Regional Airport, bus

    cheapest
    1. Fly from Denver (DEN) to Gainesville Regional Airport (GNV)plane plane DEN - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 30m
    $139–575

  3. Bus via Houston

    1. Take the bus from Denver Union Station to Fort Worth Downtownbus bus
    2. Take the bus from Fort Worth to Hyatt Regency Houstonbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Lake Citybus bus
    37h 34m
    $384–521

  4. Train, bus

    1. Take the train from Denver to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    2d 9h
    $742–1,655

  5. Drive 1,628.1 mi

    1. Drive from Denver to Lake Citycar car 1,628.1 mi
    28h 4m
    $298–430

  6. Fly to Orlando, bus

    1. Fly from Denver (DEN) to Orlando (MCO)plane plane DEN - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    11h 36m
    $236–609

  7. Fly to Valdosta, bus

    1. Fly from Denver (DEN) to Valdosta (VLD)plane plane DEN - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 26m
    $162–615

  8. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    4. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    38h 55m
    $248–492

Denver to Lake City by train and bus

Calendar7Weekly Services
Duration2d 9hAverage Duration
Ticket$742Cheapest Price
See schedules

Questions & Answers

Map of how to get from Denver to Lake City.ExpandLaunch map view
  • Distance: 1,546.1 mi
  • Duration: 8h 33m

What companies run services between Denver, CO, USA and Lake City, FL, USA?

You can take a bus from Denver Union Station to Lake City via Fort Worth Downtown, Fort Worth, Hyatt Regency Houston, Theater District Rusk EB, Magnolia Park Transit Center EB, Houston - Harrisburg Blvd, and Lake City in around 37h 34m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers