What is the cheapest way to get from Denver to Mayo Clinic?

The cheapest way to get from Denver to Mayo Clinic is to drive which costs $150 - $220 and takes 14h 15m.

What is the fastest way to get from Denver to Mayo Clinic?

The fastest way to get from Denver to Mayo Clinic is to fly and bus which takes 6h 46m and costs $140 - $330.

Is there a direct bus between Denver and Mayo Clinic?

No, there is no direct bus from Denver station to Mayo Clinic. However, there are services departing from Denver Union Station and arriving at Rochester via Des Moines and Minneapolis. The journey, including transfers, takes approximately 21h 48m.

How far is it from Denver to Mayo Clinic?

The distance between Denver and Mayo Clinic is 723 miles. The road distance is 835.7 miles.

How do I travel from Denver to Mayo Clinic without a car?

The best way to get from Denver to Mayo Clinic without a car is to bus which takes 21h 48m and costs $190 - $300.

How long does it take to get from Denver to Mayo Clinic?

It takes approximately 6h 50m to get from Denver to Mayo Clinic, including transfers.

Where do I catch the Denver to Mayo Clinic bus from?

Denver to Mayo Clinic bus services, operated by Greyhound USA, depart from Denver Union Station.

Bus or fly from Denver to Mayo Clinic?

The best way to get from Denver to Mayo Clinic is to fly which takes 6h 50m and costs $75 - $440. Alternatively, you can bus, which costs $190 - $300 and takes 21h 48m.

Where does the Denver to Mayo Clinic bus arrive?

Denver to Mayo Clinic bus services, operated by Greyhound USA, arrive at Des Moines station.

Can I drive from Denver to Mayo Clinic?

Yes, the driving distance between Denver to Mayo Clinic is 836 miles. It takes approximately 14h 15m to drive from Denver to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 50+ hotels available in Mayo Clinic.

Denver to Mayo Clinic - 8 ways to travel via train, plane, bus, and car

There are 8 ways to get from Denver to Mayo Clinic by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Rochester
best
1. Fly from Denver (DEN) to Rochester (RST)plane DEN - RST
6h 50m
$75–432
Bus
1. Take the bus from Denver Union Station to Des Moinesbus
2. Take the bus from Des Moines to Minneapolis Bus Stationbus
3. Take the bus from Minneapolis to Rochesterbus
21h 48m
$193–291
Train, bus
1. Take the train from Denver to Chicago Union Stationtrain
2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
3. Take the bus from Madison to Rochesterbus
28h 26m
$646–1,006
Drive 830.8 mi
1. Drive from Denver to Mayo Cliniccar 830.8 mi
14h 15m
$152–219
Fly to Minneapolis–Saint Paul International Airport, bus
1. Fly from Denver (DEN) to Minneapolis–Saint Paul International Airport (MSP)plane DEN - MSP
2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
6h 46m
$144–325
Fly to The Eastern Iowa Airport, drive
1. Fly from Denver (DEN) to The Eastern Iowa Airport (CID)plane DEN - CID
2. Drive from Cedar-Rapids-Airport-CID to Mayo Cliniccar
7h
$100–431
Fly to Fort Dodge Municipal Airport, drive
1. Fly from Denver (DEN) to Fort Dodge Municipal Airport (FOD)plane DEN - FOD
2. Drive from Fort Dodge Municipal Airport (FOD) to Mayo Cliniccar
6h 56m
$94–410
Bus via Sioux Falls
1. Take the bus from Denver to Omahabus
2. Take the bus from Omaha to Sioux Fallsbus
3. Take the bus from Sioux Falls to Minneapolis-St. Paulbus
4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
26h 32m
$325–414

Denver to Mayo Clinic by bus and foot

7Weekly Services

21h 48mAverage Duration

$193Cheapest Price

See schedules

Comparing Your Travel Options

Map of how to get from Denver to Mayo Clinic.

Launch map view

Distance: 718.6 mi
Duration: 6h 50m

What companies run services between Denver, CO, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and two other airlines fly from Denver (DEN) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Denver Union Station to Mayo Clinic via Des Moines, Minneapolis, and Rochester in around 21h 48m.

Airlines

Train operators

Bus operators

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